来自大鼠腹水肝癌细胞的谷氨酰胺依赖性氨甲酰磷酸合成酶与天冬氨酸氨甲酰转移酶和二氢乳清酸酶的多酶复合物。纯化、分子特性及有限蛋白酶解 - Suppr

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超能文献

Multi-enzyme complex of glutamine-dependent carbamoyl-phosphate synthetase with aspartate carbamoyltransferase and dihydroorotase from rat ascites-hepatoma cells. Purification, molecular properties and limited proteolysis.

作者信息

Mori M, Tatibana M

出版信息

Eur J Biochem. 1978 May 16;86(2):381-8. doi: 10.1111/j.1432-1033.1978.tb12320.x.

DOI:10.1111/j.1432-1033.1978.tb12320.x

PMID:26565

Abstract

摘要

相似文献

Multi-enzyme complex of glutamine-dependent carbamoyl-phosphate synthetase with aspartate carbamoyltransferase and dihydroorotase from rat ascites-hepatoma cells. Purification, molecular properties and limited proteolysis.来自大鼠腹水肝癌细胞的谷氨酰胺依赖性氨甲酰磷酸合成酶与天冬氨酸氨甲酰转移酶和二氢乳清酸酶的多酶复合物。纯化、分子特性及有限蛋白酶解

Eur J Biochem. 1978 May 16;86(2):381-8. doi: 10.1111/j.1432-1033.1978.tb12320.x.

A multienzyme complex of carbamoyl-phosphate synthase (glutamine): aspartate carbamoyltransferase: dihydoorotase (rat ascites hepatoma cells and rat liver).氨甲酰磷酸合酶（谷氨酰胺）：天冬氨酸氨甲酰转移酶：二氢乳清酸酶多酶复合物（大鼠腹水肝癌细胞和大鼠肝脏）

Methods Enzymol. 1978;51:111-20. doi: 10.1016/s0076-6879(78)51019-7.

Purification of homogeneous glutamine-dependent carbamyl phosphate synthetase from ascites hepatoma cells as a complex with aspartate transcarbamylase and dihydroorotase.从腹水肝癌细胞中纯化出与天冬氨酸转氨甲酰酶和二氢乳清酸酶形成复合物的纯质谷氨酰胺依赖性氨甲酰磷酸合成酶。

J Biochem. 1975 Jul;78(1):239-42.

Purification of a multifunctional protein bearing carbamyl-phosphate synthase, aspartate transcarbamylase, and dihydroorotase enzyme activities from mutant hamster cells.从突变仓鼠细胞中纯化一种具有氨甲酰磷酸合成酶、天冬氨酸转氨甲酰酶和二氢乳清酸酶活性的多功能蛋白质。

Methods Enzymol. 1978;51:121-34. doi: 10.1016/s0076-6879(78)51020-3.

Control of pyrimidine biosynthesis in the Ascaris ovary: regulatory properties of glutamine-dependent carbamoyl-phosphate synthetase and copurification of the enzyme with aspartate carbamoyltransferase and dihydroorotase.蛔虫卵巢中嘧啶生物合成的调控：谷氨酰胺依赖性氨甲酰磷酸合成酶的调节特性以及该酶与天冬氨酸氨甲酰转移酶和二氢乳清酸酶的共纯化

Mol Biochem Parasitol. 1980 Mar;1(1):55-68. doi: 10.1016/0166-6851(80)90041-9.

The catalytic mechanism of hamster dihydroorotase.仓鼠二氢乳清酸酶的催化机制。

Adv Exp Med Biol. 1994;370:549-53. doi: 10.1007/978-1-4615-2584-4_116.

CAD overexpression in mammalian cells.CAD在哺乳动物细胞中的过表达。

Adv Exp Med Biol. 1998;431:481-5. doi: 10.1007/978-1-4615-5381-6_95.

Immunochemical analysis of the domain structure of CAD, the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells.对CAD结构域的免疫化学分析，CAD是一种在哺乳动物细胞中启动嘧啶生物合成的多功能蛋白质。

J Biol Chem. 1985 Dec 15;260(29):15840-9.

Glutamine-dependent carbamoyl-phosphate synthetase and control of pyrimidine biosynthesis in the parasitic helminth Schistosoma mansoni.谷氨酰胺依赖性氨甲酰磷酸合成酶与曼氏血吸虫嘧啶生物合成的调控

Comp Biochem Physiol B. 1979;63(4):511-5. doi: 10.1016/0305-0491(79)90055-5.

Developmental regulation of the first three enzymes of pyrimidine biosynthesis in Drosophila melanogaster.黑腹果蝇嘧啶生物合成途径中前三种酶的发育调控

Dev Biol. 1978 Nov;67(1):1-10. doi: 10.1016/0012-1606(78)90295-6.

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Proteolytically induced changes in the molecular form of the carbamyl phosphate synthetase-uracil-aspartate transcarbamylase complex coded for by the URA2 locus in Saccharomyces cerevisiae.由酿酒酵母URA2基因座编码的氨甲酰磷酸合成酶-尿嘧啶-天冬氨酸转氨甲酰酶复合物分子形式的蛋白水解诱导变化。

J Bacteriol. 1981 Nov;148(2):659-69. doi: 10.1128/jb.148.2.659-669.1981.

Organization of a multifunctional protein in pyrimidine biosynthesis. A domain hypersensitive to proteolysis.嘧啶生物合成中多功能蛋白的组织。对蛋白水解敏感的结构域。

Biochem J. 1984 Jan 15;217(2):435-40. doi: 10.1042/bj2170435.

Partial cDNA sequence to a hamster gene corrects defect in Escherichia coli pyrB mutant.仓鼠基因的部分cDNA序列可纠正大肠杆菌pyrB突变体中的缺陷。

Proc Natl Acad Sci U S A. 1983 Nov;80(22):6897-901. doi: 10.1073/pnas.80.22.6897.

Genetic and biochemical properties of revertants at the rudimentary locus in Drosophila melanogaster.黑腹果蝇 rudimentary 基因座回复突变体的遗传与生化特性

Mol Gen Genet. 1981;183(2):270-6. doi: 10.1007/BF00270628.

Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains.对启动哺乳动物细胞嘧啶生物合成的多功能蛋白质进行的可控蛋白水解：离散结构域的证据。

Proc Natl Acad Sci U S A. 1981 Nov;78(11):6647-51. doi: 10.1073/pnas.78.11.6647.

Evidence that mammalian glutamine-dependent carbamyl phosphate synthetase arose through gene fusion.哺乳动物谷氨酰胺依赖性氨甲酰磷酸合成酶通过基因融合产生的证据。

J Mol Evol. 1992 Sep;35(3):217-22. doi: 10.1007/BF00178597.

Alteration in structure of multifunctional protein from Chinese hamster ovary cells defective in pyrimidine biosynthesis.来自嘧啶生物合成缺陷的中国仓鼠卵巢细胞的多功能蛋白质结构改变。

Proc Natl Acad Sci U S A. 1979 Apr;76(4):1731-5. doi: 10.1073/pnas.76.4.1731.

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