阿尔茨海默病有预防方法吗？
Does prevention for Alzheimer's disease exist?
作者信息
Brucki Sonia Maria Dozzi
机构信息
MD, PhD, Neurologist from the Cognitive and Behavioral Neurology Group (University of São Paulo); Psychobiology Department (Federal University of São Paulo); Hospital Santa Marcelina, São Paulo, SP, Brazil.
出版信息
Dement Neuropsychol. 2009 Jul-Sep;3(3):209-213. doi: 10.1590/S1980-57642009DN30300006.
The prevention of Alzheimer's disease is a growing public health concern amidst an ageing population. Meanwhile, there is no effective or curative treatment available where prevention could greatly reduce health costs. This review was based on reports of potential preventive factors, including modifiable lifestyle factors, as well as preventive pharmacological strategies. Although the present review was not systematic, the reports selected from PubMed using "Alzheimer's disease" and "prevention" as key-words, allow us to affirm that pursuing a healthy lifestyle; physical, cognitive, leisure activities; good social engagement; a high consumption of fish, low consumption of dietary fat and moderate consumption of wine, and control of vascular risk factors appear to be potential factors for delaying dementia.
在人口老龄化的背景下，阿尔茨海默病的预防日益成为公共卫生关注的焦点。与此同时，目前尚无有效的治疗方法，而预防措施可大幅降低医疗成本。本综述基于潜在预防因素的报告，包括可改变的生活方式因素以及预防性药物策略。尽管本综述并非系统性综述，但通过使用“阿尔茨海默病”和“预防”作为关键词从PubMed中筛选出的报告，使我们能够确认，保持健康的生活方式、进行体育锻炼、认知活动、休闲活动、良好的社交参与、大量食用鱼类、低脂肪饮食以及适量饮酒，以及控制血管危险因素似乎是延缓痴呆症的潜在因素。
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