Engelhardt Eliasz, Tocquer Carla, André Charles, Moreira Denise Madeira, Okamoto Ivan Hideyo, Cavalcanti José Luiz de Sá
Full Professor (retired) - UFRJ, Coordinator of the Cognitive Neurology and Behavior Sector, INDC, CDA/IPUB, UFRJ, Rio de Janeiro RJ, Brazil.
Neurologist, Masters and PhD in Neuropsychology, Claude Bernard University, France.
Dement Neuropsychol. 2011 Oct-Dec;5(4):251-263. doi: 10.1590/S1980-57642011DN05040003.
Vascular dementia (VaD) is the most prevalent form of secondary dementia and the second most common of all dementias. The present paper aims to define guidelines on the basic principles for treating patients with suspected VaD (and vascular cognitive impairment - no dementia) using an evidence-based, systematized approach. The knowledge used to define these guidelines was retrieved from searches of several databases (Medline, Scielo, Lilacs) containing scientific articles, systematic reviews, meta-analyses, largely published within the last 15 years or earlier when pertinent. Information retrieved and selected for relevance was used to analyze diagnostic criteria and to propose a diagnostic system encompassing diagnostic criteria, anamnesis, as well as supplementary and clinical exams (neuroimaging and laboratory). Wherever possible, instruments were selected that had versions previously adapted and validated for use in Brazil that take into account both schooling and age. This task led to proposed protocols for supplementary exams based on degree of priority, for application in clinical practice and research settings.
血管性痴呆(VaD)是继发性痴呆最常见的形式,也是所有痴呆中第二常见的类型。本文旨在采用循证、系统化的方法,为疑似血管性痴呆(及血管性认知障碍-无痴呆)患者的治疗基本原则制定指南。用于定义这些指南的知识来自对多个数据库(Medline、Scielo、Lilacs)的检索,这些数据库包含科学文章、系统评价、荟萃分析,大多发表于过去15年或更早的相关时期。检索到并筛选出的相关信息用于分析诊断标准,并提出一个涵盖诊断标准、病史以及补充检查和临床检查(神经影像学和实验室检查)的诊断系统。只要有可能,就选择那些先前已在巴西进行了改编和验证的工具,同时考虑到教育程度和年龄。这项工作产生了基于优先级的补充检查建议方案,可应用于临床实践和研究环境。