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体重指数对韩国老年人死亡率的预后影响。

Prognostic effect of body mass index to mortality in Korean older persons.

机构信息

Department of Family Medicine, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Korea.

Department of Family Medicine, Hallym University, College of Medicine, Chuncheon, Korea.

出版信息

Geriatr Gerontol Int. 2018 Apr;18(4):538-546. doi: 10.1111/ggi.13213. Epub 2017 Dec 7.

Abstract

AIM

Body mass index (BMI) is regarded as a predictor of life expectancy and a determinant of mortality. However, the effect of age on BMI-related mortality remains unclear. The aim of the present study was to examine the prognostic effect of BMI to mortality risk among Korean older persons.

METHODS

Data were collected from the Korean National Health Insurance Services' Senior Cohort database. This study analyzed the data of 79 341 men and 91 298 women aged ≥65 years who underwent health examinations in the 2007 fiscal year. Individual mortality was identified 5 years after 2008. The participants were stratified into seven groups according to basal BMI. Hazard ratios of death were calculated through Cox proportional hazards model after adjusting for age, sex, smoking status, exercise, alcohol intake and income.

RESULTS

During the 5-year follow up, 11 651 men and 7 235 women died. In both sexes, a lower BMI had a higher hazard ratio (HR), but the trend of increasing HR at high BMI was not clear. For men, the lowest HR was 0.79 (95% CI 0.71-0.87) at a BMI of 27.5-30.0 kg/m . For women, the lowest HR was 0.84 (95% CI 0.78-0.91) at a BMI of 25.0-27.5 kg/m . For both sexes, the relative mortality risk was associated with a lower BMI.

CONCLUSIONS

A high BMI is not associated with increased mortality in older adults aged ≥65 years, whereas a lower BMI is associated with an increased mortality risk in later life in this population. Geriatr Gerontol Int 2018; 18: 538-546.

摘要

目的

体重指数(BMI)被认为是预测预期寿命和死亡率的指标。然而,年龄对 BMI 相关死亡率的影响尚不清楚。本研究旨在探讨 BMI 对韩国老年人死亡率风险的预测作用。

方法

数据来自韩国国家健康保险服务的老年人队列数据库。本研究分析了 2007 财年接受体检的 79341 名男性和 91298 名女性≥65 岁老年人的数据。2008 年后的 5 年内确定了个体的死亡率。根据基础 BMI 将参与者分为七组。通过 Cox 比例风险模型调整年龄、性别、吸烟状况、运动、饮酒和收入后,计算死亡的风险比(HR)。

结果

在 5 年的随访期间,有 11651 名男性和 7235 名女性死亡。在男性和女性中,较低的 BMI 具有较高的 HR,但高 BMI 时 HR 增加的趋势并不明显。对于男性,BMI 在 27.5-30.0kg/m 时 HR 最低为 0.79(95%CI 0.71-0.87)。对于女性,BMI 在 25.0-27.5kg/m 时 HR 最低为 0.84(95%CI 0.78-0.91)。对于两性,相对死亡率风险与较低的 BMI 相关。

结论

对于≥65 岁的老年人,高 BMI 与死亡率增加无关,而低 BMI 与该人群晚年的死亡风险增加相关。老年医学与老年病学杂志 2018;18:538-546。

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