Lai S M, Zhang Z X, Alter M, Sobel E
Department of Neurology, Temple University Hospital, Philadelphia, Pa.
Neuroepidemiology. 1989;8(2):56-67. doi: 10.1159/000110167.
Mortality attributed to multiple sclerosis (MS) was analyzed for 35 countries around the world using World Health Organization reports from 1965 to 1984. Trends were plotted for the United States and Canada, for various regions of Europe, Israel, South America, Asia, Australia and some Pacific countries. In general, MS mortality has declined steadily in North America and most of western Europe as well as in countries with a western culture but has remained stable or increased in eastern and northern Europe. Although several Mediterranean countries reported a recent increased frequency of MS, it was not (yet?) evident in mortality data. Intensive prospective surveillance of MS frequency trends in selected regions of the world will determine the validity of the trends based on mortality.
利用世界卫生组织1965年至1984年的报告，对全球35个国家归因于多发性硬化症（MS）的死亡率进行了分析。绘制了美国、加拿大、欧洲各地区、以色列、南美洲、亚洲、澳大利亚及一些太平洋国家的趋势图。总体而言，在北美、西欧大部分地区以及具有西方文化的国家，MS死亡率稳步下降，但在东欧和北欧则保持稳定或上升。尽管几个地中海国家报告近期MS发病率有所增加，但在死亡率数据中尚未体现。对世界选定地区MS发病率趋势进行密集的前瞻性监测，将确定基于死亡率的趋势的有效性。
