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新生牛犊的矿化作用有助于其健康,改善抗氧化系统,并减少细菌感染。

Mineralization in newborn calves contributes to health, improve the antioxidant system and reduces bacterial infections.

机构信息

Department of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Chapecó, Santa Catarina (SC), Brazil.

Department of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Chapecó, Santa Catarina (SC), Brazil; Graduate Program of Animal Science, UDESC, Chapecó, Santa Catarina (SC), Brazil; Department of Biochemistry and Molecular Biology, Universidade Federal de Santa (UFSM), Santa Maria (RS), Brazil.

出版信息

Microb Pathog. 2018 Jan;114:344-349. doi: 10.1016/j.micpath.2017.12.012. Epub 2017 Dec 6.

Abstract

The first phase of life of dairy calves has elevated mortality indices linked with low immunity and sanitary challenges, mainly bacterial infections are involved in the pathogenesis of diarrhea, the leading cause of death. Also, other important problem is the nutritional deficiencies, such as the mineral deficiency. Thus, the aim of this study was to evaluate whether an intramuscular mineral supplementation based on selenium, copper, potassium, magnesium and phosphorus possess beneficial effects on health of dairy calves. For this, ten calves were divided in two groups: the group A was supplemented with injectable mineral, while the group B was used as control group (without mineral supplementation). The mineral complex was administrated via intramuscularly at dose of 3 mL/animal on days 2 and 14 post-birth. The total blood was collected on days 2, 10, 20 and 30 of life of animals in order to analyze the antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)), blood count and seric biochemistry linked with proteic, lipid and carbohydrate metabolism. Feces samples were also collected on days 10, 20 and 30 of life of animals to perform the total bacterial count, parasitological exam and fecal consistency score. Moreover, the weight and corporal temperature were also evaluated. The mineral supplementation presented beneficial properties to calves from birth to the 30th of life through the increase on activity of antioxidant enzymes, improvement of immunity, and avoiding problems linked with diarrhea and anemia, can be considered an interesting approach to prevent these alterations linked with high mortality in the period of life.

摘要

奶牛犊牛生命的第一阶段存在较高的死亡率指数,这与低免疫力和卫生挑战有关,主要涉及细菌感染的腹泻是导致死亡的主要原因。此外,其他重要问题是营养缺乏,如矿物质缺乏。因此,本研究旨在评估基于硒、铜、钾、镁和磷的肌肉内矿物质补充是否对奶牛犊牛的健康有益。为此,将 10 头小牛分为两组:A 组接受注射矿物质补充剂,B 组作为对照组(不补充矿物质)。矿物质复合物在出生后第 2 天和第 14 天以 3 毫升/动物的剂量通过肌肉内给药。在动物生命的第 2、10、20 和 30 天采集总血样,以分析抗氧化酶(过氧化氢酶(CAT)、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GPx))、血液计数和与蛋白质、脂质和碳水化合物代谢相关的血清生物化学。还在动物生命的第 10、20 和 30 天采集粪便样本,以进行总细菌计数、寄生虫检查和粪便稠度评分。此外,还评估了体重和体温。矿物质补充从出生到 30 天对小牛具有有益特性,通过增加抗氧化酶的活性、改善免疫力以及避免与腹泻和贫血相关的问题,可以被认为是预防生命早期高死亡率相关变化的一种有趣方法。

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