Takahashi Hisashi, Ueshima Taiki, Goto Daiki, Kimura Tadashi, Yuki Natsuko, Inoue Yasuo, Yoshioka Akira
Departments of Neurology, National Hospital Organization Maizuru Medical Center, Japan.
Departments of Neurosurgery, National Hospital Organization Maizuru Medical Center, Japan.
Intern Med. 2018 Feb 15;57(4):591-594. doi: 10.2169/internalmedicine.9115-17. Epub 2017 Dec 8.
A 63-year-old man developed vomiting, paraparesis, dysuria, bulbar palsy, and orthostatic hypotension over a period of 5 months. Neuroradiological examinations showed a swollen lower brainstem with a dural arteriovenous fistula at the craniocervical junction (DAVF-CCJ). A steroid was administered intravenously in the hospital to relieve brainstem edema. A few hours later, however, the patient developed acute tetraparesis with respiratory failure. Recently, there have been several reports describing the acute worsening of paraparesis in patients with a spinal dural arteriovenous fistula after steroid treatment. In addition to these reports, the present case suggests the risk of administering steroids to patients with DAVF-CCJ, especially those with brainstem dysfunction.
一名63岁男性在5个月的时间里出现了呕吐、双下肢轻瘫、排尿困难、延髓麻痹和体位性低血压。神经放射学检查显示下脑干肿胀,颅颈交界处存在硬脑膜动静脉瘘(DAVF-CCJ)。在医院静脉注射类固醇以减轻脑干水肿。然而,数小时后,患者出现急性四肢轻瘫并伴有呼吸衰竭。最近,有几份报告描述了脊髓硬脑膜动静脉瘘患者在接受类固醇治疗后双下肢轻瘫急性加重的情况。除了这些报告外,本病例提示对DAVF-CCJ患者,尤其是存在脑干功能障碍的患者使用类固醇存在风险。