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在动脉血运重建试验中期分析后,布莱士·帕斯卡与冠状动脉搭桥手术中使用多条动脉移植物的证据

Blaise Pascal and the evidence on the use of multiple arterial grafts for coronary artery bypass surgery after the interim analysis of the Arterial Revascularization Trial.

作者信息

Gaudino Mario F L, Ruel Marc, Taggart David P

机构信息

Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York City, New York, USA.

Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Canada.

出版信息

Curr Opin Cardiol. 2018 Mar;33(2):245-248. doi: 10.1097/HCO.0000000000000492.

DOI:10.1097/HCO.0000000000000492
PMID:29227299
Abstract

PURPOSE OF REVIEW

After the publication of the interim analysis of the ART, we review the contradiction between the large numbers of observational studies published on the course of over 25 years and the randomized trials comparing the use of single versus multiple arterial grafts for coronary bypass surgery.

RECENT FINDINGS

The Arterial Revascularization Trial (ART) found no difference in survival and event-free survival at 5 years between patients randomized to receive one or two internal thoracic arteries at the time of surgery.

SUMMARY

At the moment, there is evidence that arterial grafts have higher patency rate than venous grafts and a possible protective effect on the coronary circulation. Arterial grafts are still a reasonable choice, especially in patients with long life expectancy. Further studies and the final results of ART are needed.

摘要

综述目的

在发表了动脉血运重建术(ART)的中期分析之后,我们对25多年来发表的大量关于冠状动脉搭桥手术中使用单根与多根动脉移植物的观察性研究与随机试验之间的矛盾进行了综述。

最新发现

动脉血运重建术(ART)发现,随机分组在手术时接受一根或两根胸廓内动脉的患者在5年时的生存率和无事件生存率没有差异。

总结

目前,有证据表明动脉移植物的通畅率高于静脉移植物,并且对冠状动脉循环可能有保护作用。动脉移植物仍然是一个合理的选择,特别是对于预期寿命长的患者。需要进一步的研究以及ART的最终结果。

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1
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引用本文的文献

1
Bilateral internal thoracic artery use in coronary bypass surgery: is there a benefit?双侧胸廓内动脉用于冠状动脉搭桥手术:有获益吗?
Indian J Thorac Cardiovasc Surg. 2018 Dec;34(Suppl 3):230-233. doi: 10.1007/s12055-018-0693-4. Epub 2018 Aug 3.
2
Percutaneous coronary intervention versus coronary bypass surgery for unprotected left main disease: a meta-analysis of randomized controlled trials.经皮冠状动脉介入治疗与冠状动脉搭桥手术治疗无保护左主干病变:随机对照试验的荟萃分析
Ann Cardiothorac Surg. 2018 Jul;7(4):454-462. doi: 10.21037/acs.2018.06.05.