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不稳定住房女性的医用大麻使用与其他药物使用之间的关联。

Associations between medical cannabis and other drug use among unstably housed women.

机构信息

Department of Psychiatry and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.

Department of Psychiatry and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.

出版信息

Int J Drug Policy. 2018 Feb;52:45-51. doi: 10.1016/j.drugpo.2017.11.009. Epub 2017 Dec 9.

Abstract

BACKGROUND

Several studies suggest that U.S. state-level legalization of cannabis for medical purposes may be associated with reductions in opioid use; yet its relationship with stimulant use, particularly in high-risk populations like unstably housed women, has received less attention. The purpose of this study was to estimate independent associations between medical and non-medical use of cannabis and use of stimulants and opioids among unstably housed women.

METHODS

Cross-sectional data were analyzed from 245 women in the SHADOW study, a community based cohort in San Francisco, CA, in which HIV+ women were oversampled (126 HIV+ and 119 HIV-).

RESULTS

Compared to no cannabis use in the past 6 months (51%), non-medical cannabis use (28%) was associated with a higher adjusted odds of using stimulants (Adjusted Odds Ratio [AOR]=4.34, 95% confidence interval [CI]: 2.17-8.70) and opioids (AOR=3.81, 95% CI: 1.78-8.15). Compared to no cannabis use, medical cannabis use (21%) was not significantly associated with stimulant or opioid use. Compared to non-medical cannabis use, however, medical cannabis use was associated with lower adjusted odds of using stimulants (AOR=0.42, 95% CI: 0.18-0.96). These associations were not modified by HIV status.

CONCLUSIONS

Associations between use of cannabis and "street drugs" depend on whether the cannabis is obtained through a medical context. Interventions, research, and policy considering the influence of cannabis on the use of other drugs may benefit by distinguishing between medical and non-medical cannabis use.

摘要

背景

多项研究表明,美国将医用大麻合法化可能与阿片类药物使用量减少有关;然而,医用大麻与兴奋剂使用之间的关系,特别是在像不稳定居住的女性这样的高风险人群中,却较少受到关注。本研究旨在评估医用和非医用大麻使用与不稳定居住女性使用兴奋剂和阿片类药物之间的独立关联。

方法

分析了来自加利福尼亚州旧金山社区为基础的 SHADOW 研究中的 245 名女性的横断面数据,该研究对 HIV 阳性女性进行了过采样(126 名 HIV 阳性和 119 名 HIV 阴性)。

结果

与过去 6 个月内无大麻使用(51%)相比,非医用大麻使用(28%)与使用兴奋剂(调整后的优势比 [AOR]=4.34,95%置信区间 [CI]:2.17-8.70)和阿片类药物(AOR=3.81,95% CI:1.78-8.15)的调整后比值更高。与无大麻使用相比,医用大麻使用(21%)与兴奋剂或阿片类药物的使用无显著关联。然而,与非医用大麻使用相比,医用大麻使用与使用兴奋剂的调整后比值较低相关(AOR=0.42,95% CI:0.18-0.96)。这些关联不受 HIV 状态的影响。

结论

大麻使用与“街头毒品”之间的关联取决于大麻是否通过医疗途径获得。考虑到大麻对其他药物使用的影响的干预措施、研究和政策,通过区分医用和非医用大麻使用可能会受益。

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