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在活动性人造主动脉瓣心内膜炎中使用 Perceval 无缝线瓣膜。

Use of the Perceval Sutureless Valve in Active Prosthetic Aortic Valve Endocarditis.

机构信息

Department of Cardiac Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Department of Cardiac Surgery, Hospital Gregorio Marañón, Madrid, Spain.

出版信息

Ann Thorac Surg. 2018 Apr;105(4):1168-1174. doi: 10.1016/j.athoracsur.2017.11.031. Epub 2017 Dec 9.

Abstract

BACKGROUND

Surgical treatment of active prosthetic aortic valve endocarditis presents a challenge for cardiac surgeons because of tissue friability and destruction caused by infection. Sutureless prostheses, such as the Perceval S (LivaNova, Saluggia, Italy), have emerged as an option among the different surgical approaches for these complicated cases.

METHODS

This study presents data from 9 patients who underwent aortic valve re-replacement with the Perceval S because of active prosthetic aortic valve endocarditis between January 2014 and August 2016. Hemodynamic performance (mean transprosthetic gradient and type of aortic regurgitation) was assessed intraoperatively after weaning from cardiopulmonary bypass, at discharge, and to 6 months postoperatively.

RESULTS

After weaning from cardiopulmonary bypass, cases 1 and 3 through 6 had no or trivial aortic regurgitation, cases 7 and 8 presented with trivial to mild regurgitation, case 9 showed mild intraprosthetic regurgitation, and case 2 had mild periprosthetic regurgitation. Cases 4 and 7 died of septic shock and multiorgan failure in the perioperative period. In the remaining patients, severity of aortic regurgitation maintained practically invariable at discharge compared with intraoperative results. These 7 patients did well at 6-month follow-up, with good clinical and hemodynamic performance of the Perceval S prosthesis. The median of mean transprosthetic gradient was 11 mm Hg (interquartile range: 10 to 12 mm Hg). Only patient 2 showed mild periprosthetic regurgitation; patient 9 showed mild intraprosthetic insufficiency, and the remaining patients had no or trivial regurgitation.

CONCLUSIONS

The sutureless Perceval S valve is a reasonable alternative for surgical treatment of prosthetic aortic valve endocarditis.

摘要

背景

由于感染导致的组织脆弱和破坏,对于心脏外科医生来说,积极的人工主动脉瓣心内膜炎的手术治疗是一个挑战。无缝线假体,如 Perceval S(LivaNova,Saluggia,意大利),已成为这些复杂病例的不同手术方法的选择之一。

方法

本研究介绍了 2014 年 1 月至 2016 年 8 月期间,因活动人工主动脉瓣心内膜炎而接受 Perceval S 主动脉瓣再次置换的 9 例患者的数据。在脱离体外循环后、出院时和术后 6 个月时,评估血流动力学性能(平均跨瓣梯度和主动脉瓣反流类型)。

结果

在脱离体外循环后,病例 1 和 3 至 6 例没有或轻微的主动脉瓣反流,病例 7 和 8 例呈现轻微至轻度反流,病例 9 显示轻度瓣内反流,病例 2 显示轻度瓣周反流。病例 4 和 7 在围手术期死于感染性休克和多器官衰竭。在其余患者中,与术中结果相比,出院时主动脉瓣反流的严重程度基本保持不变。这 7 例患者在 6 个月的随访中表现良好,Perceval S 假体的临床和血流动力学性能良好。平均跨瓣梯度中位数为 11mmHg(四分位距:10 至 12mmHg)。只有患者 2 显示轻度瓣周反流;患者 9 显示轻度瓣内不足,其余患者无或轻微反流。

结论

无缝线的 Perceval S 瓣膜是治疗人工主动脉瓣心内膜炎的一种合理选择。

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