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八段锦对2型糖尿病的影响：随机对照试验的系统评价和荟萃分析

Baduanjin Exercise for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

作者信息

Wen Junmao, Lin Tong, Cai Yinhe, Chen Qianying, Chen Yuexuan, Ren Yueyi, Weng Senhui, Wang Boqing, Ji Shuliang, Wu Wei

机构信息

Guangzhou University of Chinese Medicine, Guangzhou, China.

Department of Cardiovascular Disease, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Evid Based Complement Alternat Med. 2017;2017:8378219. doi: 10.1155/2017/8378219. Epub 2017 Oct 19.

DOI:10.1155/2017/8378219
PMID:29234435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5671720/
Abstract

OBJECTIVE

To investigate the effects of Baduanjin exercise for type 2 diabetes mellitus.

METHODS

Literature retrieval was performed in several databases, including PubMed, EMBASE, Cochrane Library, CNKI, Wanfang Data Information Site, CBM, and VIP from inception to April 2017. Randomized controlled trials on evaluating the effects of Baduanjin exercise were identified. The primary outcomes were glycosylated hemoglobin, fasting blood-glucose, and postprandial plasma glucose. Review Manager 5.2 (RevMan 5.2) and Stata V.13.0 software were conducted for data analysis.

RESULTS

The results of the meta-analysis indicated that the effects of type 2 diabetes mellitus were favoring Baduanjin plus conventional therapy, when compared with the routine treatment. Baduanjin plus conventional therapy lowered the level of glycosylated hemoglobin, fasting blood-glucose, postprandial plasma glucose, TC, TG, and LDL-C and improved HDL-C. Adverse events were not mentioned in all included studies. No publication bias was detected by Begg's and Egger's test and no single study affected the overall result by influence analysis.

CONCLUSIONS

Evidence from meta-analysis suggested that Baduanjin exercise plus conventional therapy has a positive effect on type 2 diabetes mellitus. However, more rigorously designed and large sample RCTs are required to confirm the efficacy and safety in further studies.

摘要

目的

探讨八段锦锻炼对2型糖尿病的影响。

方法

检索多个数据库，包括PubMed、EMBASE、Cochrane图书馆、中国知网、万方数据信息服务平台、中国生物医学文献数据库和维普资讯，检索时间从建库至2017年4月。纳入评估八段锦锻炼效果的随机对照试验。主要结局指标为糖化血红蛋白、空腹血糖和餐后血糖。采用Review Manager 5.2（RevMan 5.2）和Stata V.13.0软件进行数据分析。

结果

Meta分析结果表明，与常规治疗相比，八段锦联合常规治疗对2型糖尿病的疗效更佳。八段锦联合常规治疗可降低糖化血红蛋白、空腹血糖、餐后血糖、总胆固醇、甘油三酯和低密度脂蛋白胆固醇水平，并提高高密度脂蛋白胆固醇水平。所有纳入研究均未提及不良事件。Begg检验和Egger检验未检测到发表偏倚，影响分析显示没有单个研究影响总体结果。

结论

Meta分析证据表明，八段锦锻炼联合常规治疗对2型糖尿病有积极作用。然而，需要更严格设计的大样本随机对照试验来进一步证实其疗效和安全性。

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