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一只患有感染的犬的肺乳头状腺癌

Pulmonary papillary adenocarcinoma with infection in a dog.

作者信息

Maniam Rathiymaler, Selvarajah Gayathri Thevi, Mazlan Mazlina, Lung Than Leslie Thian

机构信息

Department of Veterinary Laboratory Diagnosis, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Malaysia.

Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, Serdang 43400, Malaysia.

出版信息

Med Mycol Case Rep. 2017 Dec 1;19:25-29. doi: 10.1016/j.mmcr.2017.11.005. eCollection 2018 Mar.

Abstract

Papillary adenocarcinoma of the lungs is the most common primary lung adenocarcinoma, with the feature of papillary-like structure formation by cells. A dog was presented with the primary complaint of vomiting, hyporexia and increased respiratory effort. Thoracic radiography revealed increased soft tissue radiopacity of the right cranial lung lobe suggestive of possible consolidation or collapsed lung lobe, with generalised miliary nodular pattern throughout the other lung fields. The dog was euthanized humanely and necropsy was performed. Histopathology confirmed the diagnosis of primary pulmonary lung neoplasm (papillary adenocarcinoma) with infection identified through fungal culture and PCR. There have been several reports on humans and dogs with fungal infections that often mimic or coexist with pulmonary neoplasm. This is the first documented report of isolated from a lung neoplasm in a dog in Malaysia.

摘要

肺乳头状腺癌是最常见的原发性肺腺癌,其特征是细胞形成乳头状结构。一只狗因呕吐、食欲减退和呼吸费力等主要症状前来就诊。胸部X光检查显示右肺前叶软组织密度增加,提示可能存在实变或肺叶塌陷,其他肺野有弥漫性粟粒状结节影。对该犬实施了安乐死并进行了尸检。组织病理学确诊为原发性肺肿瘤(乳头状腺癌),通过真菌培养和聚合酶链反应鉴定出感染。已有多篇关于人类和犬类真菌感染的报道,这些感染常与肺肿瘤相似或并存。这是马来西亚首次有文献记载从犬肺肿瘤中分离出(某种真菌)的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e70/5723271/9c874746f869/gr1.jpg

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