Mellinger Jessica L, Volk Michael L
Division of Gastroenterology, University of Michigan Hospitals, 1500 Medical Center Dr., 3912 Taubman Center, SPC 5362, Ann Arbor, MI 48109-5362, USA.
Division of Gastroenterology and Transplantation Institute, Loma Linda University Medical, Loma Linda University Health, 25865 Barton Road, Suite 101, Loma Linda, CA 92354, USA.
Alcohol Alcohol. 2018 Mar 1;53(2):173-177. doi: 10.1093/alcalc/agx105.
Alcohol-related liver disease (ALD) is the second leading cause of liver transplantation performed in the USA and Europe. We aimed to provide a narrative review of the major ethical issues governing transplantation for ALD.
We performed a narrative review of the ethical concepts in organ allocation for ALD, including alcoholic hepatitis.
Ethical concerns regarding organ allocation for ALD involve issues of urgency, utility and justice. Post-transplant outcomes for ALD patients are good and ethical considerations limiting organs solely because of alcohol etiology do not bear scrutiny.
ALD will continue to be a major cause for liver failure. The main criteria for transplant in ALD should be the patient's risk of return to harmful drinking, alongside standard assessments of physical and psychosocial fitness for transplant.
酒精性肝病(ALD)是美国和欧洲进行肝移植的第二大主要原因。我们旨在对ALD移植的主要伦理问题进行叙述性综述。
我们对ALD(包括酒精性肝炎)器官分配中的伦理概念进行了叙述性综述。
关于ALD器官分配的伦理问题涉及紧迫性、效用和公平性。ALD患者移植后的结果良好,仅因酒精病因限制器官的伦理考量经不起推敲。
ALD将继续是肝衰竭的主要原因。ALD移植的主要标准应是患者恢复有害饮酒的风险,以及对移植身体和心理社会适应性的标准评估。