泮库溴铵过敏：一例病例报告。

Pancuronium allergy: a case report.

作者信息

Patriarca G, Nucera E, Schiavino D, Romano A, Di Rienzo V, Pellegrino S, Fais G

机构信息

Department of Allergology, Catholic University, Rome, Italy.

出版信息

Br J Anaesth. 1989 Feb;62(2):210-2. doi: 10.1093/bja/62.2.210.

DOI:10.1093/bja/62.2.210

PMID:2923771

Abstract

A case of anaphylactic shock to pancuronium bromide is described in which a type I immunological reaction occurred. A 33-yr-old male anaesthetist, with no family or personal history of allergy, collapsed soon after induction of anaesthesia. The drugs used included fentanyl, droperidol, thiopentone and pancuronium. Diffuse erythema occurred, with probable cardiac arrest. The patient was treated with cardiac massage, sympathomimetics and cortisone, and made a complete recovery. Examination (skin tests, passive transfer according to Prausnitz and Küstner, in vitro lymphocyte transformation test, total IgE assay) revealed that the allergic reaction was to pancuronium bromide.

摘要

本文描述了一例因溴化潘库溴铵导致过敏反应休克的病例，该反应为I型免疫反应。一名33岁的男性麻醉师，无家族或个人过敏史，在麻醉诱导后不久突然晕倒。所用药物包括芬太尼、氟哌利多、硫喷妥钠和溴化潘库溴铵。出现了弥漫性红斑，可能发生了心脏骤停。患者接受了心脏按摩、拟交感神经药和皮质激素治疗，并完全康复。检查（皮肤试验、普劳斯尼茨-屈斯特纳被动转移试验、体外淋巴细胞转化试验、总IgE测定）显示，过敏反应是由溴化潘库溴铵引起的。