Farré Adriana, Tirado-Muñoz Judit, Torrens Marta
Institute of Neuropsychiatry and Addictions, Parc de Salut Mar de Barcelona, Barcelona.
Hospital del Mar Medical Research Institute (IMIM).
Addict Disord Their Treat. 2017 Dec;16(4):180-186. doi: 10.1097/ADT.0000000000000118. Epub 2017 Aug 4.
Mood and substance use disorders (SUDs) are mental conditions that are highly prevalent in the general population. Cooccurrence of major depression and SUD, also known as dual depression, is very common in the field of substance addiction. Sex differences are found in both major depression and SUD. This review, after presenting the state of the art of dual depression as regards prevalence, ethiopathologic mechanisms, and clinical aspects, is focused on dual depression in women. An overview of some potential factors associated with the sex gap in dual depression such as injecting, sexual risk behavior, intimate partner violence, and the reproductive cycle is presented.
情绪和物质使用障碍（SUDs）是在普通人群中高度流行的精神疾病。重度抑郁症与物质使用障碍的共病，也称为双重抑郁症，在物质成瘾领域非常常见。在重度抑郁症和物质使用障碍中均发现了性别差异。本综述在介绍了双重抑郁症在患病率、病因病理机制和临床方面的最新情况后，重点关注女性的双重抑郁症。本文概述了一些与双重抑郁症性别差异相关的潜在因素，如注射、性风险行为、亲密伴侣暴力和生殖周期。
