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高危亚组成员身份是腰椎前路融合术后30天发病率的一个预测指标。

High-Risk Subgroup Membership Is a Predictor of 30-Day Morbidity Following Anterior Lumbar Fusion.

作者信息

Bronheim Rachel S, Kim Jun S, Di Capua John, Lee Nathan J, Kothari Parth, Somani Sulaiman, Phan Kevin, Cho Samuel K

机构信息

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Prince of Wales Private Hospital, Sydney, Australia.

出版信息

Global Spine J. 2017 Dec;7(8):762-769. doi: 10.1177/2192568217696691. Epub 2017 Apr 11.

DOI:10.1177/2192568217696691
PMID:29238640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5721989/
Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

To determine if membership in a high-risk subgroup is predictive of morbidity and mortality following anterior lumbar fusion (ALF).

METHODS

The American College of Surgeons National Surgical Quality Improvement Program database was utilized to identify patients undergoing ALF between 2010 and 2014. Multivariate analysis was utilized to identify high-risk subgroup membership as an independent predictor of postoperative complications.

RESULTS

Members of the elderly (≥65 years) (OR = 1.3, = .02) and non-Caucasian (black, Hispanic, other) (OR = 1.7, < .0001) subgroups were at greater risk for a LOS ≥5 days. Obese patients (≥30 kg/m ) were at greater risk for an operative time ≥4 hours (OR = 1.3, = .005), and wound complications (OR = 1.8, = .024) compared with nonobese patients. Emergent procedures had a significantly increased risk for LOS ≥5 days (OR = 4.9, = .021), sepsis (OR = 14.8, = .018), and reoperation (OR = 13.4, < .0001) compared with nonemergent procedures. Disseminated cancer was an independent risk factor for operative time ≥4 hours (OR = 8.4, < .0001), LOS ≥5 days (OR = 15.2, < .0001), pulmonary complications (OR = 7.4, = .019), and postoperative blood transfusion (OR = 3.1, = .040).

CONCLUSIONS

High-risk subgroup membership is an independent risk factor for morbidity following ALF. These groups should be targets for aggressive preoperative optimization, and quality improvement initiatives.

摘要

研究设计

回顾性队列研究。

目的

确定高危亚组的成员身份是否可预测腰椎前路融合术(ALF)后的发病率和死亡率。

方法

利用美国外科医师学会国家外科质量改进计划数据库,识别2010年至2014年间接受ALF的患者。采用多变量分析确定高危亚组成员身份作为术后并发症的独立预测因素。

结果

老年(≥65岁)亚组(OR = 1.3,P = 0.02)和非白种人(黑人、西班牙裔、其他)亚组(OR = 1.7,P < 0.0001)的患者住院时间≥5天的风险更高。与非肥胖患者相比,肥胖患者(≥30 kg/m²)手术时间≥4小时的风险更高(OR = 1.3,P = 0.005),伤口并发症的风险更高(OR = 1.8,P = 0.024)。与非急诊手术相比,急诊手术患者住院时间≥5天(OR = 4.9,P = 0.021)、败血症(OR = 14.8,P = 0.018)和再次手术(OR = 13.4,P < 0.0001)的风险显著增加。播散性癌症是手术时间≥4小时(OR = 8.4,P < 0.0001)、住院时间≥5天(OR = 15.2,P < 0.0001)、肺部并发症(OR = 7.4,P = 0.019)和术后输血(OR = 3.1,P = 0.040)的独立危险因素。

结论

高危亚组成员身份是ALF术后发病的独立危险因素。这些群体应成为积极术前优化和质量改进举措的目标。

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