Thalhammer T, Peterlik M, Graf J
Institute of General and Experimental Pathology, University of Vienna, Austria.
Biochim Biophys Acta. 1989 Mar 13;979(3):371-4. doi: 10.1016/0005-2736(89)90259-9.
In isolated basolateral and canalicular rat liver plasma membrane vesicles the membrane potential (measured with DiS-C2 (5] varied with transmembrane concentration gradients of Na+, K+ and Cl- revealing the following ion permeabilities: basolateral vesicles: PNa/PK: 0.76, PCl/PK: 0.45 and canalicular vesicles: PNa/PK: 0.69, PCl/PK: 0.56. The data indicate a permselectivity of PK greater than PNa greater than PCl for both membranes.
在分离出的大鼠肝基底外侧膜和胆小管膜囊泡中，膜电位（用DiS-C2(5)测量）随Na+、K+和Cl-的跨膜浓度梯度而变化，显示出以下离子通透性：基底外侧膜囊泡：PNa/PK为0.76，PCl/PK为0.45；胆小管膜囊泡：PNa/PK为0.69，PCl/PK为0.56。数据表明，两种膜对K+的通透性选择性均大于Na+大于Cl-。
