David R. Cheriton School of Computer Science, University of Waterloo, Waterloo, ON, Canada.
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P.R. China.
Proteomics. 2018 Jan;18(2). doi: 10.1002/pmic.201700319. Epub 2017 Dec 29.
Deep learning has revolutionized research in image processing, speech recognition, natural language processing, game playing, and will soon revolutionize research in proteomics and genomics. Through three examples in genomics, protein structure prediction, and proteomics, we demonstrate that deep learning is changing bioinformatics research, shifting from algorithm-centric to data-centric approaches.
深度学习已经彻底改变了图像处理、语音识别、自然语言处理、游戏等领域的研究,并且很快将彻底改变蛋白质组学和基因组学的研究。通过基因组学、蛋白质结构预测和蛋白质组学中的三个示例,我们证明深度学习正在改变生物信息学研究,从以算法为中心的方法转变为以数据为中心的方法。