Edgar Bruce A, Grewal Savraj S
Nature. 2017 Dec 14;552(7684):182-183. doi: 10.1038/d41586-017-07435-x.
The evolutionarily conserved enzyme RNA polymerase III is a driver of protein synthesis and cell growth. It emerges that partial suppression of this essential enzyme extends lifespan in yeast, roundworms and flies.
进化上保守的酶RNA聚合酶III是蛋白质合成和细胞生长的驱动因素。事实证明,对这种必需酶的部分抑制可延长酵母、蛔虫和果蝇的寿命。