Berti Aldo Fabrizio, Zafar Atif, Ikram Asad, Calder Christopher S, Sorte Danielle Eckart
1 Department of Neurology, 1104 University of New Mexico , Albuquerque, USA.
2 Departments of Radiology and Neurosurgery, 1104 University of New Mexico , Albuquerque, USA.
Interv Neuroradiol. 2018 Apr;24(2):178-182. doi: 10.1177/1591019917747879. Epub 2017 Dec 14.
When multiple, recurrent infarcts occur in spite of maximal medical management, the level of suspicion for atypical vascular injury should be heightened. We present a case of a patient who presented with recurrent posterior circulation infarcts despite optimized medical management. On imaging, he was found to have external anatomical vertebral artery muscular and/or osseous compression leading to repetitive vascular injury and strokes. Recurrent intimal injury and vertebral artery to intracranial emboli despite anticoagulation and subsequent dual antiplatelet therapy necessitated definitive operative management. Surgical bypass, external surgical decompression, reconstructive endovascular, and deconstructive endovascular techniques were carefully considered. A deconstructive endovascular approach was chosen as the least morbid option. The use of endovascular plugs such as a microvascular plug provides a quick and effective means of achieving a therapeutic parent artery occlusion in lieu of traditional coil occlusion. Although reserved as a last resort, parent artery occlusion can be a viable option to treat recurrent strokes, particularly in a nondominant vertebral artery.
尽管采取了最大程度的药物治疗仍发生多发性、复发性梗死时,应提高对非典型血管损伤的怀疑程度。我们报告一例患者,尽管进行了优化的药物治疗,仍出现复发性后循环梗死。影像学检查发现,他存在椎动脉外部解剖结构的肌肉和/或骨质压迫,导致反复的血管损伤和中风。尽管进行了抗凝治疗及随后的双联抗血小板治疗,仍出现反复的内膜损伤和椎动脉至颅内的栓子,因此需要进行确定性手术治疗。仔细考虑了外科搭桥、外科外减压、重建性血管内治疗和破坏性血管内治疗技术。选择破坏性血管内治疗方法作为创伤最小的选择。使用微血管栓塞等血管内栓塞物可提供一种快速有效的方法,以实现治疗性的供血动脉闭塞,替代传统的弹簧圈闭塞。尽管作为最后手段保留,但供血动脉闭塞可能是治疗复发性中风的可行选择,特别是在非优势椎动脉中。