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动态椎动脉狭窄继发缺血性卒中:病例报告及文献综述

Ischemic Stroke Secondary to Dynamic Vertebral Artery Stenosis: Case Report and Review of the Literature.

作者信息

Bukhari Mohammed K, Alghamdi Saeed A

机构信息

Neurology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.

Research, King Abdullah International Medical Research Center, Jeddah, SAU.

出版信息

Cureus. 2021 Dec 4;13(12):e20167. doi: 10.7759/cureus.20167. eCollection 2021 Dec.

Abstract

Ischemic stroke secondary to dynamic vertebral artery stenosis or occlusion, also known as "bow hunter's syndrome," is a rare stroke mechanism. We report a case of a 24-year-old man with multiple hereditary exostosis (MHE) diagnosed at childhood. His first presentation to a neurologist was due to neck pain and clinical syndrome suggestive of ischemia in the vertebrobasilar territory. A therapeutic occlusion was done successfully without complication. The patient was discharged two days later on aspirin alone. In follow up one year later he continued to be symptom free. Moreover, this stroke mechanism has been reported extensively in the literature in isolation or secondary to many underlying diseases. In total, there are 168 cases reported in the published English literature, in either case reports or small series. In this review, we found that by far, vertebral artery occlusion at the atlanto-axial (C1-2) level dominated most reported cases. The most frequent presentation that led to further investigation was syncope or pre-syncope provoked by head rotation to one side. To our knowledge, there is no previous report of any stroke syndrome related to MHE before our case. In this paper, we report the first case secondary to MHE and review the literature up to date since the first reported case in 1952.

摘要

继发于动态椎动脉狭窄或闭塞的缺血性卒中,也称为“弓猎综合征”,是一种罕见的卒中机制。我们报告一例24岁男性病例,其在儿童期被诊断为多发性遗传性骨软骨瘤(MHE)。他首次就诊于神经科医生是因为颈部疼痛以及提示椎基底动脉供血区缺血的临床综合征。成功实施了治疗性闭塞且无并发症。患者两天后仅服用阿司匹林出院。一年后的随访中他持续无症状。此外,这种卒中机制在文献中已有广泛报道,单独出现或继发于许多基础疾病。在已发表的英文文献中,无论是病例报告还是小系列研究,总共报道了168例。在本综述中,我们发现到目前为止,寰枢椎(C1 - 2)水平的椎动脉闭塞在大多数报道病例中占主导地位。导致进一步检查的最常见表现是向一侧转头诱发的晕厥或先兆晕厥。据我们所知,在我们的病例之前没有任何与MHE相关的卒中综合征的报道。在本文中,我们报告了首例继发于MHE的病例,并回顾了自1952年首例报道病例以来的最新文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4daa/8724019/e32330da4463/cureus-0013-00000020167-i01.jpg

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