Sanotskaia N V, Polikarpov V V, Matsievskiĭ D D
Biull Eksp Biol Med. 1989 Feb;107(2):157-61.
The ultrasonic method was used in acute experiments on cats with open chest under artificial lung ventilation to obtain blood flow in low-lobar pulmonary artery and vein, the blood pressure in pulmonary artery, as well as the left atrial pressure in fat (olive oil) and mechanical (Lycopodium spores) pulmonary embolism. It is shown that pulmonary embolism produces the decrease in the blood flow in pulmonary artery and vein, the increase of the pressure in pulmonary artery and left atria, the increase of lung vessels resistance. The decrease is observed of systemic arterial pressure, bradycardia, and extrasystole. After 5-10 min the restoration of arterial pressure and heart rhythm occur and partial restoration of blood flow in pulmonary artery and vein. In many experiments the blood flow in vein outdoes that in the artery--it allows to suppose the increase of the blood flow in bronchial artery. After 60-90 min there occur sudden decrease of systemic arterial pressure, the decrease of the blood flow in pulmonary artery and vein. The pressure in pulmonary artery and resistance of pulmonary vessels remain high. Pulmonary edema developed in all animals. The death occurs in 60-100 min after the beginning of embolism.
在人工肺通气下对开胸猫进行急性实验,采用超声法获取低叶肺动脉和肺静脉的血流、肺动脉血压以及脂肪(橄榄油)和机械性(石松子孢子)肺栓塞时的左心房压力。结果表明,肺栓塞会导致肺动脉和肺静脉血流减少、肺动脉和左心房压力升高、肺血管阻力增加。同时观察到体循环动脉压降低、心动过缓和期前收缩。5 - 10分钟后,动脉压和心律恢复,肺动脉和肺静脉血流部分恢复。在许多实验中,静脉血流超过动脉血流——这表明支气管动脉血流增加。60 - 90分钟后,体循环动脉压突然降低,肺动脉和肺静脉血流减少。肺动脉压力和肺血管阻力仍保持较高水平。所有动物均发生肺水肿。栓塞开始后60 - 100分钟动物死亡。