Suppr超能文献

[高频肺通气对肺动脉微栓塞时肺循环及体循环的影响]

[The effect of high-frequency ventilation of the lungs on the pulmonary and systemic circulations in microembolism of the pulmonary artery].

作者信息

Sanotskaia N V, Vyzhigina M A, Matsievskiĭ D D, Luk'ianov M V, Aleĭnikov S O

出版信息

Biull Eksp Biol Med. 1993 Nov;116(11):466-9.

PMID:8312529
Abstract

The linear and volumetric blood flow velocity in the ascending aorta and pulmonary artery conus, right-left ventricular ejection balance, pulmonary and femoral arterial blood pressures, pulmonary microcirculation in fat pulmonary microembolism induced during the routine and high-frequency jet lung ventilation (HFJLV) were studied by ultrasonic techniques in acute experiments on cats with open chest under nembutal narcosis. Pulmonary microembolism was shown to resulted in 487 and 252% increases in pulmonary vascular resistance during the routine and HFJLVs, respectively. There were also 167 and 127% increases in mean pulmonary pressure and 60 and 34% decreases in the volumetric velocity of pulmonary blood flow. The linear velocity of pulmonary blood flow was unchanged with routine lung ventilation, whereas it decreased by 68% with HFJLV. Microembolism impaired the balance between right and left ventricular ejections with blood being redistributed into the greater circulation. The imbalance lasted 5-7 min during HFJLV, while with the routine lung ventilation it was preserved up to the end of the experiment, and systemic blood pressure and total peripheral vascular resistance decreased. Alveolar edema developed in interstitial pulmonary edema. The animals' death occurred 40-60 min later.

摘要

在戊巴比妥麻醉下对开胸猫进行急性实验,运用超声技术研究了常规通气和高频喷射肺通气(HFJLV)过程中脂肪性肺微栓塞时升主动脉和肺动脉圆锥内的线性和容积性血流速度、左右心室射血平衡、肺和股动脉血压以及肺微循环情况。结果显示,在常规通气和HFJLV过程中,肺微栓塞分别导致肺血管阻力增加487%和252%。平均肺动脉压也分别升高167%和127%,肺血流容积速度分别降低60%和34%。常规肺通气时肺血流线性速度未变,而HFJLV时降低了68%。微栓塞破坏了左右心室射血平衡,血液重新分布到体循环。HFJLV过程中这种失衡持续5 - 7分钟,而常规肺通气时这种失衡一直持续到实验结束,体循环血压和总外周血管阻力降低。肺泡水肿发展为间质性肺水肿。动物在40 - 60分钟后死亡。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验