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[脂溶性和水溶性抗氧化剂在肝微粒体脂质过氧化过程中对细胞色素P-450系统的保护作用]

[Protective action of fat- and water-soluble antioxidants on the cytochrome P-450 system during lipid peroxidation in liver microsomes].

作者信息

Serbinova E A, Kadiĭska M B, Tiurin V A, Kagan V E, Stoĭchev Ts S

出版信息

Biull Eksp Biol Med. 1989 Feb;107(2):187-8.

PMID:2923975
Abstract

The protective effects of alpha-tocopherol, carnosine and their mixture on monooxygenase system during lipid peroxidation in liver microsome membranes were studied. It was shown that for optimal protection effect of cytochrome P-450 system the mixture of water and liposoluble antioxidants is required.

摘要

研究了α-生育酚、肌肽及其混合物对肝微粒体膜脂质过氧化过程中单一加氧酶系统的保护作用。结果表明,为使细胞色素P - 450系统获得最佳保护效果,需要水溶性和脂溶性抗氧化剂的混合物。

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