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克罗恩病。

Crohn's disease.

机构信息

Servicio de Medicina Digestiva, Hospital Clínico Universitario de Valencia, Valencia, España.

Servicio de Medicina Digestiva, Hospital Clínico Universitario de Valencia, Valencia, España.

出版信息

Med Clin (Barc). 2018 Jul 13;151(1):26-33. doi: 10.1016/j.medcli.2017.10.036. Epub 2017 Dec 13.

Abstract

Crohn's disease is a chronic inflammatory bowel disease of unknown etiology associated with an impaired immune response, with periods of activity and remission. It is characterised by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea, which can seriously affect patients' quality of life. The increasing incidence and prevalence of the disease in our area has had a large impact on clinical practice, with the rapid development of diagnostic and therapeutic techniques. To reduce the risk of complications, primary care physicians and gastroenterologists should be familiar with the management of the disease.

摘要

克罗恩病是一种病因不明的慢性炎症性肠病,与免疫应答受损有关,具有活动期和缓解期。其特征为节段性和透壁性病变,可以累及整个胃肠道,从口腔到肛门。最常见的症状是腹痛和腹泻,这会严重影响患者的生活质量。在我们地区,这种疾病的发病率和患病率不断增加,对临床实践产生了重大影响,诊断和治疗技术也迅速发展。为了降低并发症的风险,初级保健医生和胃肠病学家应该熟悉该疾病的管理。

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