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炎症性肠病患者眼部肠外表现发病率的分析:一项系统评价

Analysis of the Incidence of Ocular Extraintestinal Manifestations in Inflammatory Bowel Disease Patients: A Systematic Review.

作者信息

Songel-Sanchis Bruno, Cosín-Roger Jesús

机构信息

Departamento de Farmacología and CIBERehd, Facultad de Medicina, Universidad de Valencia, Av. Blasco Ibáñez, 15, 46010 Valencia, Spain.

出版信息

Diagnostics (Basel). 2024 Dec 14;14(24):2815. doi: 10.3390/diagnostics14242815.

Abstract

: Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, primarily affects the gastrointestinal tract. Additionally, extraintestinal manifestations may occur in the liver, musculoskeletal system and eyes. Its etiology remains unknown, and further research is required in order to develop pharmacological drugs which achieve complete remission of the pathology. : The aim of this study was to analyze the incidence of ocular extraintestinal manifestations in IBD patients. : A total of six searches were carried out on the medical publication server "" in June and July 2024, using different keywords; a total of 323 results were obtained, of which 34 were finally selected for study. : Ocular extraintestinal manifestations in IBD patients are more common in the anterior pole of the eye, with uveitis, scleritis and episcleritis being the most usual ones. In the case of the posterior pole, the most common manifestations are posterior uveitis and optic neuritis. : The incidence of ocular complications whose origin is inflammatory, such as uveitis, scleritis, episcleritis and neuritis, is higher than that of complications of non-inflammatory origin.

摘要

炎症性肠病(IBD),包括克罗恩病和溃疡性结肠炎,主要影响胃肠道。此外,还可能出现肝脏、肌肉骨骼系统和眼部的肠外表现。其病因尚不清楚,需要进一步研究以开发能使病情完全缓解的药物。

本研究的目的是分析炎症性肠病患者眼部肠外表现的发生率。

2024年6月和7月,在医学出版物服务器“”上共进行了六次搜索,使用了不同的关键词;共获得323条结果,最终选择了34条进行研究。

炎症性肠病患者的眼部肠外表现在眼的前极更为常见,葡萄膜炎、巩膜炎和表层巩膜炎最为常见。在后极的情况下,最常见的表现是后葡萄膜炎和视神经炎。

起源于炎症的眼部并发症,如葡萄膜炎、巩膜炎、表层巩膜炎和神经炎的发生率高于非炎症性起源的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aa1/11675585/494930f2ed81/diagnostics-14-02815-g001.jpg

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