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[用 ICO 系列单克隆抗体可检测到的抗原在半固体琼脂中形成粒细胞和巨噬细胞集落的细胞表面的表达]

[The expression of antigens, detectable with ICO-series monoclonal antibodies, on the surfaces of cells forming granulocyte and macrophage colonies in semiliquid agar].

作者信息

Savel'eva E V, Kharlamova L A, Baryshnikov A Iu, Agafonov V A, Tupitsyn N N

出版信息

Eksp Onkol. 1989;11(1):46-8.

PMID:2924710
Abstract

The expression of antigens on granulocyte-macrophagal colony-forming cells of patients with nonhematological diseases was studied. Treatment of bone marrow cells with murine monoclonal antibodies ICO-1 and ICO-11 led to statistically significant inhibition of the number of growing colonies. Monoclonal antibodies ICO-02, ICO-10, ICO-GM-1 and ICO-G-2 had no such effect.

摘要

对非血液系统疾病患者粒细胞-巨噬细胞集落形成细胞上抗原的表达进行了研究。用鼠单克隆抗体ICO-1和ICO-11处理骨髓细胞,导致生长集落数量出现统计学上的显著抑制。单克隆抗体ICO-02、ICO-10、ICO-GM-1和ICO-G-2没有这种作用。

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