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计算机干预措施减少大麻使用的效果:系统评价和荟萃分析。

The efficacy of computerized interventions to reduce cannabis use: A systematic review and meta-analysis.

机构信息

Universitat Pompeu Fabra-Universitat Autònoma de Barcelona, Barcelona 08003, Spain.

Addiction Research Group, IMIM-Institut Hospital del Mar d' Investigacions Mèdiques, Barcelona 08003, Spain.

出版信息

Addict Behav. 2018 Apr;79:52-60. doi: 10.1016/j.addbeh.2017.11.045. Epub 2017 Dec 7.

Abstract

BACKGROUND AND AIMS

Cannabis is the most widely consumed illicit drug. Although it is too early to confirm the impact of legalization, the use of cannabis appears to be on the rise in some countries due to its authorization for medical/recreational purposes. Among different types of therapeutic approaches to reduce cannabis use, computerized interventions are becoming a new treatment option. To assess their efficacy, a systematic review and meta-analysis was conducted.

METHODS

A systematic review and meta-analysis was performed employing randomized controlled clinical trials indexed in MEDLINE and PsycINFO. The principal outcome measure was cannabis use, and the secondary one was the use of other substances during interventions. A subgroup analysis was conducted by length of follow-up, number of sessions, age group, type of analysis, and type of control condition.

RESULTS

The meta-analysis included nine studies with 2963 participants. Computerized interventions resulted in significant reductions in the use of cannabis (standardized mean difference [SMD]: -0.19; 95% CI: -0.26, -0.11) and other substances (SMD: -0.27; 95% CI: -0.46, -0.08).

CONCLUSIONS

Computerized interventions examined in the present study reduced the frequency of cannabis and other substance use. Limitations included the recalculation of dichotomous and continuous data as SMD and the lower number of studies included in the secondary outcome. Computerized interventions could be a viable option to reduce cannabis use.

摘要

背景与目的

大麻是最广泛使用的非法药物。尽管现在确认合法化的影响还为时过早,但由于其被授权用于医疗/娱乐目的,大麻的使用在一些国家似乎呈上升趋势。在减少大麻使用的不同类型的治疗方法中,计算机干预正在成为一种新的治疗选择。为了评估其疗效,进行了系统评价和荟萃分析。

方法

采用 MEDLINE 和 PsycINFO 索引的随机对照临床试验进行系统评价和荟萃分析。主要结局指标是大麻使用情况,次要结局指标是干预期间其他物质的使用情况。根据随访时间、疗程数、年龄组、分析类型和对照条件类型进行亚组分析。

结果

荟萃分析包括 9 项研究,共 2963 名参与者。计算机干预显著减少了大麻(标准化均数差 [SMD]:-0.19;95%置信区间:-0.26,-0.11)和其他物质的使用(SMD:-0.27;95%置信区间:-0.46,-0.08)。

结论

本研究中检查的计算机干预措施降低了大麻和其他物质的使用频率。局限性包括将二分类和连续数据重新计算为 SMD,以及次要结局中包含的研究数量较少。计算机干预可能是减少大麻使用的可行选择。

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