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一名HIV阳性患者的乳腺外佩吉特病。

Extramammary Paget's disease in an HIV-positive patient.

作者信息

Căruntu Constantin, Zurac Sabina Andrada, Jugulete GheorghiŢă, Boda Daniel

机构信息

Department of Pathology, "Colentina" Clinical Hospital, Bucharest, Romania;

出版信息

Rom J Morphol Embryol. 2017;58(3):1009-1015.

Abstract

Extramammary Paget's disease (EMPD) is an uncommon intraepithelial carcinoma usually found as an irregular, pruritic plaque on the apocrine-rich anogenital skin. Diagnosis of EMPD is challenging due to the rarity of the disease and the uncharacteristic clinical aspect and requires histopathological confirmation. We report the case of a 62-year-old human immunodeficiency virus (HIV)-positive male, which presents with a lesion of the left part of pubic area with clinical and dermatoscopic appearance suggestive for Bowen's disease but with histopathological diagnosis of EMPD. We present pathological and immunohistochemical data to confirm the diagnosis.

摘要

乳房外佩吉特病(EMPD)是一种罕见的上皮内癌,通常表现为发生于富含顶泌汗腺的肛门生殖器皮肤的不规则、瘙痒性斑块。由于该疾病罕见且临床特征不典型,EMPD的诊断具有挑战性,需要组织病理学确诊。我们报告一例62岁男性人类免疫缺陷病毒(HIV)阳性患者,其耻骨区左侧出现一处皮损,临床及皮肤镜表现提示鲍温病,但组织病理学诊断为EMPD。我们展示病理和免疫组化数据以确诊。

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