Centre for Molecular Epidemiology and Translational Research, Institute for Global Health, University College London.
The National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Blood Borne and Sexually Transmitted Infections, University College London.
Curr Opin Infect Dis. 2018 Feb;31(1):50-56. doi: 10.1097/QCO.0000000000000423.
Sexual transmission of enteric pathogens in men who have sex with men (MSM) has been described since the 1970s. Recently, an increasing number of enteric infection outbreaks have been reported in MSM. This article summarizes recent outbreaks and discusses the key issues for prevention and control.
Sexually transmissible enteric infections (STEIs) can spread rapidly and internationally within highly connected MSM populations and are often associated with antimicrobial resistance (AMR). The infections often cluster in high-risk groups of HIV-positive MSM who are more likely to engage in diverse sexual practices and chemsex, and to have multiple other sexually transmitted infections (STIs).
The roles of asymptomatic and/or persistent infection and other contextual factors in STEI transmission are not well described. STEI-associated AMR is increasing and has potential to spread rapidly in MSM, warranting further public health attention. A better understanding of the factors associated with sexual transmission will enable the development of more effective control measures. A holistic approach that promotes health and wellbeing as well as infection prevention and management is needed.
自 20 世纪 70 年代以来，人们就已经描述了男男性行为者（MSM）中的肠道病原体的性传播。最近，报告了越来越多的 MSM 中的肠道感染暴发。本文总结了最近的暴发情况，并讨论了预防和控制的关键问题。
性传播肠道感染（STEIs）可在高度相关的 MSM 人群中迅速且在国际上传播，并且通常与抗生素耐药性（AMR）相关。这些感染通常在 HIV 阳性的 MSM 高危人群中聚集，他们更有可能进行多种性行为和化学性行为，并患有多种其他性传播感染（STI）。
无症状和/或持续性感染以及其他相关因素在 STEI 传播中的作用尚未得到很好的描述。与 STEI 相关的 AMR 正在增加，并且有可能在 MSM 中迅速传播，这需要进一步引起公共卫生关注。更好地了解与性传播相关的因素将有助于制定更有效的控制措施。需要采取一种整体方法，促进健康和幸福感以及感染预防和管理。
