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经皮抗生素给药技术治疗骨髓炎概述及跟骨骨髓炎病例研究

An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and a Case Study of Calcaneal Osteomyelitis.

作者信息

Karr Jeffrey C

出版信息

J Am Podiatr Med Assoc. 2017 Nov;107(6):511-515. doi: 10.7547/13-047.

DOI:10.7547/13-047
PMID:29252017
Abstract

BACKGROUND

A percutaneous antibiotic delivery technique (PAD-T) used for the adjunctive management of osteomyelitis is presented.

METHODS

This surgical technique incorporates a calcium sulfate and hydroxyapatite (calcium phosphate) bone void filler acting as a carrier vehicle with either an antibiotic or an antifungal medicine, delivering this combination directly into the area of osteomyelitis.

RESULTS

The benefit of the PAD-T is reviewed with a case presentation of a successfully treated calcaneal osteomyelitis.

CONCLUSIONS

No previously reported PAD-T using a simple bone cortex incision in the adjunctive treatment of osteomyelitis has been reported. The PAD-T safely and effectively uses a calcium sulfate and hydroxyapatite bone void filler carrier vehicle to deliver either an antibiotic or an antifungal medicine directly into the area of osteomyelitis.

摘要

背景

介绍一种用于骨髓炎辅助治疗的经皮抗生素递送技术(PAD-T)。

方法

该手术技术采用硫酸钙和羟基磷灰石(磷酸钙)骨缺损填充剂作为载体,与抗生素或抗真菌药物结合,将这种组合直接递送至骨髓炎区域。

结果

通过一例成功治疗的跟骨骨髓炎病例展示,对PAD-T的益处进行了回顾。

结论

此前未见有关于在骨髓炎辅助治疗中使用简单骨皮质切口的PAD-T的报道。PAD-T安全有效地利用硫酸钙和羟基磷灰石骨缺损填充剂载体,将抗生素或抗真菌药物直接递送至骨髓炎区域。

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