Krimsky Sheldon
Tufts University, Medford, Massachusetts, United States of America.
PLoS Biol. 2017 Dec 18;15(12):e2002404. doi: 10.1371/journal.pbio.2002404. eCollection 2017 Dec.
After 40 years, the 1976 US Toxic Substances Control Act (TSCA) was revised under the Frank R. Lautenberg Chemical Safety for the 21st Century Act. Its original goals of protecting the public from hazardous chemicals were hindered by complex and cumbersome administrative burdens, data limitations, vulnerabilities in risk assessments, and recurring corporate lawsuits. As a result, countless chemicals were entered into commercial use without toxicological information. Few chemicals of the many identified as potential public health threats were regulated or banned. This paper explores the factors that have worked against a comprehensive and rational policy for regulating toxic chemicals and discusses whether the TSCA revisions offer greater public protection against existing and new chemicals.
40年后，1976年的美国《有毒物质控制法》（TSCA）在《弗兰克·R·劳滕伯格21世纪化学安全法》下进行了修订。其最初保护公众免受有害化学物质侵害的目标受到了复杂繁琐的行政负担、数据限制、风险评估中的漏洞以及企业反复诉讼的阻碍。结果，无数化学物质在没有毒理学信息的情况下进入商业使用。在众多被确定为潜在公共健康威胁的化学物质中，很少有受到监管或被禁止的。本文探讨了阻碍制定全面合理的有毒化学物质监管政策的因素，并讨论了TSCA的修订是否能为公众提供更好的保护，使其免受现有和新化学物质的危害。
