糖尿病性黄斑水肿患者脉络膜厚度的变化
Choroidal Thickness Change in Patients With Diabetic Macular Edema.
作者信息
Eliwa Tamer F, Hegazy Omnia S, Mahmoud Safaa S, Almaamon Tarek
出版信息
Ophthalmic Surg Lasers Imaging Retina. 2017 Dec 1;48(12):970-977. doi: 10.3928/23258160-20171130-03.
BACKGROUND AND OBJECTIVE
To evaluate subfoveal choroidal thickness (SFCT) in diabetic macular edema (DME) and its relationships.
PATIENTS AND METHODS
One hundred and six eyes were included in this prospective, nonrandomized case control study. They were divided into 37 cases of healthy, normal subjects and 69 cases of nonproliferative diabetic retinopathy (NPDR) with DME. Spectral-domain optical coherence tomography was done for all cases and analyzed to measure SFCT and central foveal thickness (CFT).
RESULTS
The SFCT was significantly thinner in the DME group (193.4 μm) than in the control group (282.6 μm) (P = .001). In the DME group, SFCT was significantly related to CFT and vision (P < .05). The cutoff point for the relationship between SFCT and vision was 228 μm below the point at which vision is affected.
CONCLUSIONS
DME is associated with a significant decrease in SFCT. SFCT is directly related to vision and foveal thickness, but it is inversely correlated to age. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:970-977.].
背景与目的
评估糖尿病性黄斑水肿（DME）患者的黄斑中心凹下脉络膜厚度（SFCT）及其相关性。
患者与方法
本前瞻性、非随机病例对照研究纳入了106只眼。将其分为37例健康正常受试者和69例患有DME的非增殖性糖尿病视网膜病变（NPDR）患者。对所有病例进行了光谱域光学相干断层扫描，并分析测量了SFCT和中心凹厚度（CFT）。
结果
DME组的SFCT（193.4μm）明显薄于对照组（282.6μm）（P = .001）。在DME组中，SFCT与CFT及视力显著相关（P < .05）。SFCT与视力之间关系的截断点为228μm，低于该点视力会受到影响。
结论
DME与SFCT显著降低有关。SFCT与视力和黄斑中心凹厚度直接相关，但与年龄呈负相关。[《眼科手术、激光与视网膜成像》。2017；48：970 - 977。]
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