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营养:阿尔茨海默病的可能治疗方法综述。

Nutrition: Review on the Possible Treatment for Alzheimer's Disease.

机构信息

Institute of Neuroscience, Zhejiang University School of Medicine, Hangzhou, China.

School of Basic Medical Sciences, Zhejiang University, Hangzhou, China.

出版信息

J Alzheimers Dis. 2018;61(3):867-883. doi: 10.3233/JAD-170874.

Abstract

Since its discovery some hundred years ago, Alzheimer's disease (AD), a neurodegenerative disease and an eminent cause of most dementia, continues to pose problems for affected families and society, especially in developed countries. With the approved medications by the Food and Drugs Administration in the United States, effectual treatment of AD apropos to the complete eradication of the disease continues to be elusive due to complexities relating to the pathophysiology of the disease. Nutrition has and continues to play a salient role in the survival of living organisms with no exception for human beings. Herein, we report the connection between nutrition and AD with particular attention to vitamins, curcumin, and the Mediterranean diet.

摘要

自一百多年前发现以来,阿尔茨海默病(AD)作为一种神经退行性疾病,也是大多数痴呆症的主要病因,它继续给患者家庭和社会带来问题,尤其是在发达国家。尽管美国食品和药物管理局批准了一些药物,但由于与疾病病理生理学相关的复杂性,针对该疾病的完全消除,有效的 AD 治疗仍然难以实现。营养在生物体的生存中一直发挥着重要作用,人类也不例外。在此,我们报告了营养与 AD 之间的联系,特别关注维生素、姜黄素和地中海饮食。

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