1 Case Western Reserve University, Cleveland, OH, USA.
J Aging Health. 2019 Apr;31(4):667-684. doi: 10.1177/0898264317745745. Epub 2017 Dec 6.
This article examines the relative importance of cancer-related and noncancer illness factors as they predict the health quality of life among older adult, long-term cancer survivors. Specifically, it examines the effects that continuing cancer symptoms and comorbidities have on functional difficulties and how they in turn affect perceptions of disability and self-rated health.
Data from an National Cancer Institute (NCI)-funded, tumor registry-based 10-year study of 321 older adult (age 60+), long-term (5+years post diagnosis) survivors of breast colorectal and prostate cancer are examined using regression analyses.
The analyses documented the independent effects of both cancer-related and age-related health factors as they contribute to explaining functional difficulties, perceptions of disability and self-rated health. Gender and racial differences in health quality of life were also identified.
The findings suggest that geriatricians, geriatric nurses, and clinical gerontologists who work with cancer survivorsneed to be aware of the ways in which both cancer and noncancer illness factors work together in producing threats to health quality of life through the extent and nature of functional impairments.
本文研究了癌症相关因素和非癌症疾病因素在预测老年长期癌症幸存者健康生活质量方面的相对重要性。具体来说，它考察了持续的癌症症状和合并症对功能障碍的影响，以及它们如何反过来影响残疾感知和自我报告的健康。
本研究的数据来自美国国立癌症研究所（NCI）资助的一项基于肿瘤登记的为期 10 年的研究，该研究纳入了 321 名年龄在 60 岁及以上的老年（5 年以上）乳腺癌、结直肠癌和前列腺癌幸存者，采用回归分析进行研究。
分析结果记录了癌症相关因素和年龄相关健康因素的独立影响，这些因素有助于解释功能障碍、残疾感知和自我报告的健康。还确定了健康生活质量的性别和种族差异。
研究结果表明，与癌症幸存者一起工作的老年病学家、老年护士和临床老年病学家需要意识到癌症和非癌症疾病因素共同作用，通过功能障碍的程度和性质对健康生活质量构成威胁的方式。
