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Synthesis and antibacterial activity of novel 3-substituted carbacephems.

作者信息

Mochida K, Ogasa T, Shimada J, Hirata T, Sato K, Okachi R

机构信息

Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.

出版信息

J Antibiot (Tokyo). 1989 Feb;42(2):283-92. doi: 10.7164/antibiotics.42.283.

DOI:10.7164/antibiotics.42.283
PMID:2925519
Abstract

A series of novel 3-heterocyclothio substituted carbacephems having phenylglycyl side chain have been prepared starting from 3-H carbacephem. The compounds exhibit better chemical stability than the corresponding cephalosporin and strong activity against Gram-negative and Gram-positive organisms including Enterococcus faecalis.

摘要

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