Synthesis and antibacterial activity of novel 3-substituted carbacephems.
作者信息
Mochida K, Ogasa T, Shimada J, Hirata T, Sato K, Okachi R
机构信息
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
出版信息
J Antibiot (Tokyo). 1989 Feb;42(2):283-92. doi: 10.7164/antibiotics.42.283.
PMID:2925519
Abstract
A series of novel 3-heterocyclothio substituted carbacephems having phenylglycyl side chain have been prepared starting from 3-H carbacephem. The compounds exhibit better chemical stability than the corresponding cephalosporin and strong activity against Gram-negative and Gram-positive organisms including Enterococcus faecalis.
摘要
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