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腹主动脉瘤封堵的变形与动力响应

Deformation and dynamic response of abdominal aortic aneurysm sealing.

机构信息

Department of Mathematical Sciences, University of Liverpool, Liverpool, UK.

Liverpool Vascular & Endovascular Service, Liverpool, UK.

出版信息

Sci Rep. 2017 Dec 18;7(1):17712. doi: 10.1038/s41598-017-17759-3.

DOI:10.1038/s41598-017-17759-3
PMID:29255200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5735182/
Abstract

Endovascular sealing is a new technique for the repair of abdominal aortic aneurysms. Commercially available in Europe since 2013, it takes a revolutionary approach to aneurysm repair through minimally invasive techniques. Although aneurysm sealing may be thought as more stable than conventional endovascular stent graft repairs, post-implantation movement of the endoprosthesis has been described, potentially leading to late complications. The paper presents for the first time a model, which explains the nature of forces, in static and dynamic regimes, acting on sealed abdominal aortic aneurysms, with references to real case studies. It is shown that elastic deformation of the aorta and of the endoprosthesis induced by static forces and vibrations during daily activities can potentially promote undesired movements of the endovascular sealing structure.

摘要

血管内封闭是一种治疗腹主动脉瘤的新技术。自 2013 年在欧洲商业化以来,它通过微创技术为动脉瘤修复带来了革命性的方法。尽管血管内封闭可能被认为比传统的血管内支架修复更稳定,但已经描述了植入后内假体的运动,可能导致晚期并发症。本文首次提出了一个模型,该模型解释了作用在密封的腹主动脉瘤上的力的性质,包括静态和动态两种状态,同时还参考了真实的案例研究。结果表明,由静态力和日常活动中的振动引起的主动脉和内假体的弹性变形可能会促进血管内封闭结构的不期望运动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/d2cba0ea450a/41598_2017_17759_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/376e5b9fee82/41598_2017_17759_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/de423f36b680/41598_2017_17759_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/739738bdaa67/41598_2017_17759_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/8ae8b0bebefa/41598_2017_17759_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/d2cba0ea450a/41598_2017_17759_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/376e5b9fee82/41598_2017_17759_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/de423f36b680/41598_2017_17759_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/739738bdaa67/41598_2017_17759_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/8ae8b0bebefa/41598_2017_17759_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df0a/5735182/d2cba0ea450a/41598_2017_17759_Fig5_HTML.jpg

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本文引用的文献

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Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial.英国血管内动脉瘤修复试验 1(EVAR 试验 1)15 年随访的血管内与开放修复腹主动脉瘤的比较:一项随机对照试验。
Lancet. 2016 Nov 12;388(10058):2366-2374. doi: 10.1016/S0140-6736(16)31135-7. Epub 2016 Oct 12.
2
Endovascular Aneurysm Sealing: Early and Midterm Results From the EVAS FORWARD Global Registry.血管内动脉瘤封堵术:EVAS FORWARD全球注册研究的早期和中期结果
J Endovasc Ther. 2016 Oct;23(5):685-92. doi: 10.1177/1526602816664365. Epub 2016 Aug 22.
3
Migration of the Nellix endoprosthesis.
J Vasc Surg. 2016 Aug;64(2):306-312. doi: 10.1016/j.jvs.2016.02.053. Epub 2016 Apr 9.
4
Endovascular Aneurysm Sealing Is Associated With Reduced Radiation Exposure and Procedure Time Compared With Standard Endovascular Aneurysm Repair.与标准血管内动脉瘤修复术相比,血管内动脉瘤封堵术可减少辐射暴露和手术时间。
J Endovasc Ther. 2016 Apr;23(2):285-9. doi: 10.1177/1526602816628283. Epub 2016 Feb 5.
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Results of the Nellix system investigational device exemption pivotal trial for endovascular aneurysm sealing.用于血管内动脉瘤封堵的Nellix系统研究性器械豁免关键试验结果。
J Vasc Surg. 2016 Jan;63(1):23-31.e1. doi: 10.1016/j.jvs.2015.07.096. Epub 2015 Oct 21.
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Late Rupture of Abdominal Aortic Aneurysm After Previous Endovascular Repair: A Systematic Review and Meta-analysis.既往血管腔内修复术后腹主动脉瘤的晚期破裂:一项系统评价和荟萃分析
J Endovasc Ther. 2015 Oct;22(5):734-44. doi: 10.1177/1526602815601405. Epub 2015 Aug 18.
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Multicenter Nellix EndoVascular Aneurysm Sealing system experience in aneurysm sac sealing.多中心 Nellix 血管内动脉瘤封堵系统在动脉瘤囊封堵方面的经验。
J Vasc Surg. 2015 Aug;62(2):290-8. doi: 10.1016/j.jvs.2015.03.031. Epub 2015 May 5.
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