Sethi Shveta, Gautam Vikas, Gupta Kirti, Suri Vanita, Angrup Archana
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
JMM Case Rep. 2017 Nov 15;4(11):e005127. doi: 10.1099/jmmcr.0.005127. eCollection 2017 Nov.
Enteric fever, caused by serotype Typhi (typhoid fever) or serotype Paratyphi A, B or C (paratyphoid fever), is a major health problem in developing countries. Vertical transmission of can cause miscarriage, still birth, preterm labour and neonatal sepsis. In the literature, many cases of vertical transmission of Typhi from mother to foetus have been reported, but there are very limited studies showing vertical transmission of Paratyphi. Here, we report a rare case of serotype Paratyphi A infection in a pregnant woman resulting in a spontaneous miscarriage. serotype Paratyphi A was isolated from placental membrane in culture. A high index of suspicion, along with timely cultures of relevant samples, like blood and stool, and timely initiation of antibiotic therapy in pregnancy could possibly save the lives of such foetuses.
伤寒热由伤寒血清型(伤寒)或甲型、乙型或丙型副伤寒血清型(副伤寒)引起,是发展中国家的一个主要健康问题。其垂直传播可导致流产、死产、早产和新生儿败血症。在文献中,已有许多关于伤寒从母亲垂直传播给胎儿的病例报道,但显示副伤寒垂直传播的研究非常有限。在此,我们报告一例罕见的孕妇甲型副伤寒血清型感染导致自然流产的病例。在培养物中从胎盘膜分离出甲型副伤寒血清型。高度的怀疑指数,连同及时对血液和粪便等相关样本进行培养,以及在孕期及时开始抗生素治疗,可能会挽救此类胎儿的生命。