Li Zhikun, Li Gengwu, Chen Chao, Li Yifan, Yang Changwei, Xu Wei, Zhu Xiaodong
Orthopedics. 2018 Jan 1;41(1):e110-e116. doi: 10.3928/01477447-20171213-04. Epub 2017 Dec 19.
This study evaluated the risk factors for dysphagia after anterior cervical spine surgery by multidimensional analysis and investigated the predictive values of these risk factors for dysphagia. The patients underwent anterior cervical spine surgery and were followed for at least 6 months. Sex, age, tracheal mobility, smoking history, implant type, C3 anterior vertebral soft tissue swelling, narrowest esophageal distance before internal fixation, cervical curvature, operative time, occurrence of fusion, number of operative segments, and highest vertebral segment were recorded. Chi-square test and logistic regression were performed to analyze the predictive value of each dimension for dysphagia. A total of 158 patients were included in this study. The mean C3 anterior vertebral soft tissue swelling was 8.8±4.5 mm, the mean narrowest esophageal distance before internal fixation was 6.9±4.4 mm, and the mean operative time was 78.5±39.2 minutes. Chi-square test results showed that age 60 years and older, female sex, internal fixation with titanium plate/titanium mesh, narrowest esophageal distance before internal fixation of less than 5 mm, and 3 operative segments indicated a relatively high incidence of dysphagia. Logistic regression analyses showed that age, sex, implant type, narrowest esophageal distance before internal fixation, and number of operative segments were all risk factors predictive of postoperative dysphagia. The area under the receiver operating characteristic curve was 0.872. Age 60 years and older, female sex, internal fixation with titanium plate/titanium mesh, narrowest esophageal distance before internal fixation of less than 5 mm, and 3 operative segments were risk factors for dysphagia after anterior cervical surgery. The regression equation may be used to predict the occurrence of dysphagia. [Orthopedics. 2018; 41(1):e110-e116.].
本研究通过多维度分析评估了颈椎前路手术后吞咽困难的风险因素,并探讨了这些风险因素对吞咽困难的预测价值。患者接受颈椎前路手术,并随访至少6个月。记录患者的性别、年龄、气管活动度、吸烟史、植入物类型、C3椎体前方软组织肿胀情况、内固定前最狭窄食管距离、颈椎曲度、手术时间、融合情况、手术节段数以及最高椎体节段。采用卡方检验和逻辑回归分析各维度对吞咽困难的预测价值。本研究共纳入158例患者。C3椎体前方软组织平均肿胀为8.8±4.5mm,内固定前最狭窄食管平均距离为6.9±4.4mm,平均手术时间为78.5±39.2分钟。卡方检验结果显示,年龄60岁及以上、女性、使用钛板/钛网内固定、内固定前最狭窄食管距离小于5mm以及3个手术节段的患者吞咽困难发生率相对较高。逻辑回归分析表明,年龄、性别、植入物类型、内固定前最狭窄食管距离以及手术节段数均为术后吞咽困难的预测风险因素。受试者工作特征曲线下面积为0.872。年龄60岁及以上、女性、使用钛板/钛网内固定、内固定前最狭窄食管距离小于5mm以及3个手术节段是颈椎前路手术后吞咽困难的风险因素。回归方程可用于预测吞咽困难的发生情况。[《骨科学》。2018年;41(1):e110 - e116。]