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浸润性乳头状乳腺癌,实性变体伴神经内分泌分化。

Invasive papillary breast carcinoma, solid variant with neuroendocrine differentiation.

作者信息

Şenel Fatma, Karaman Hatice, Eroğlu Mehtap, Tuna Ömer

机构信息

Clinic of Pathology, Kayseri Training and Research Hospital, Kayseri, Turkey.

Clinic of General Surgery, Kayseri Training and Research Hospital, Kayseri, Turkey.

出版信息

Turk J Surg. 2015 Jul 14;33(4):302-304. doi: 10.5152/UCD.2015.3074. eCollection 2017.

DOI:10.5152/UCD.2015.3074
PMID:29260140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5731571/
Abstract

Invasive papillary carcinoma, solid variant is a rarely observed breast tumor. It is encountered in patients of advanced ages and has a good prognosis. After the physical examination, mammography, and ultrasonography examinations, modified radical mastectomy were applied to the 72-year-old patient, who came to our hospital complaining of a mass in the left breast. During the macroscopic analysis, a well-limited, necrotic, and bleeding tumor with a diameter of 7 cm was found in the left breast, covering almost the whole area. The case was diagnosed as invasive papillary carcinoma, solid variant with neuroendocrine differentiation, which has been reported in the literature as a result of the histopathological and immunohistochemical analysis.

摘要

浸润性乳头状癌实性型是一种罕见的乳腺肿瘤。多见于老年患者,预后良好。体格检查、乳腺钼靶和超声检查后,对我院一位因左乳肿块前来就诊的72岁患者实施了改良根治性乳房切除术。大体分析时,在左乳发现一个边界清楚、坏死、出血的肿瘤,直径7厘米,几乎覆盖整个区域。经组织病理学和免疫组化分析,该病例诊断为伴有神经内分泌分化的浸润性乳头状癌实性型,文献中有相关报道。

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Invasive solid papillary carcinoma with neuroendocrine differentiation of the breast: a case report and literature review.乳腺具有神经内分泌分化的浸润性实性乳头状癌:一例报告及文献复习
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本文引用的文献

1
Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type.黏液性和神经内分泌乳腺癌在转录上与非特殊型浸润性导管癌不同。
Mod Pathol. 2009 Nov;22(11):1401-14. doi: 10.1038/modpathol.2009.112. Epub 2009 Jul 24.
2
Loss of myoepithelium is variable in solid papillary carcinoma of the breast.乳腺实性乳头状癌中肌上皮的缺失情况不一。
Histopathology. 2007 Nov;51(5):657-65. doi: 10.1111/j.1365-2559.2007.02849.x.
3
Solid-papillary carcinoma of the breast: clinicopathological study of 20 cases.乳腺实性乳头状癌:20例临床病理研究
Pathol Int. 2007 Jul;57(7):421-9. doi: 10.1111/j.1440-1827.2007.02118.x.
4
Myoepithelial cells in solid variant of intraductal papillary carcinoma of the breast: a potential diagnostic pitfall and a proposal of an immunohistochemical panel in the differential diagnosis with intraductal papilloma with usual ductal hyperplasia.乳腺导管内乳头状癌实性变型中的肌上皮细胞:一个潜在的诊断陷阱以及关于免疫组织化学检测组合在与伴普通型导管增生的导管内乳头状瘤鉴别诊断中的建议
Virchows Arch. 2007 May;450(5):539-47. doi: 10.1007/s00428-007-0402-y. Epub 2007 Mar 22.
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Solid papillary ductal carcinoma in situ versus usual ductal hyperplasia in the breast: a potentially difficult distinction resolved by cytokeratin 5/6.乳腺实性乳头状原位癌与普通导管增生:细胞角蛋白5/6解决的潜在难题鉴别
Hum Pathol. 2006 Jul;37(7):787-93. doi: 10.1016/j.humpath.2006.02.016. Epub 2006 May 26.
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Clinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomas.乳腺实性乳头状癌及相关浸润性癌的临床病理分析
Am J Surg Pathol. 2006 Apr;30(4):501-7. doi: 10.1097/00000478-200604000-00011.
7
Spindle cell ductal carcinoma in situ. An unusual variant of ductal intra-epithelial neoplasia that simulates ductal hyperplasia or a myoepithelial proliferation.原位梭形细胞导管癌。一种不寻常的导管上皮内瘤变变体,可模拟导管增生或肌上皮增殖。
Virchows Arch. 2001 Jul;439(1):70-7. doi: 10.1007/s004280100446.
8
Solid papillary carcinoma of the breast. A form of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma.乳腺实性乳头状癌。一种具有内分泌分化的导管内癌,常与黏液癌相关。
Am J Surg Pathol. 1995 Nov;19(11):1237-44. doi: 10.1097/00000478-199511000-00003.