美国田纳西州 2017 年甲型流感病毒（H7N9）的哺乳动物发病机制和传播
Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017.
出版信息
Emerg Infect Dis. 2018 Jan;24(1):149-152. doi: 10.3201/eid2401.171574.
Abstract
Infections with low pathogenicity and highly pathogenic avian influenza A(H7N9) viruses affected poultry in 4 states in the southeastern United States in 2017. We evaluated pathogenicity and transmission of representative viruses in mouse and ferret models and examined replication kinetics in human respiratory tract cells. These viruses can cause respiratory infections in mammalian models.
摘要
2017 年，低致病性和高致病性禽流感 A(H7N9)病毒感染了美国东南部 4 个州的家禽。我们评估了这些病毒在小鼠和雪貂模型中的致病性和传播性，并研究了其在人呼吸道细胞中的复制动力学。这些病毒可以在哺乳动物模型中引起呼吸道感染。
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