Radiation Physics Department, Queen's Centre for Oncology and Haematology, Castle Hill Hospital, Hull and East Yorkshire Hospitals NHS Trust, Castle Road, Hull, HU16 5JQ, United Kingdom. Faculty of Science, University of Hull, Cottingham Road, Hull, HU6 7RX, United Kingdom.
Phys Med Biol. 2018 Jan 16;63(2):025025. doi: 10.1088/1361-6560/aaa307.
Effective detective quantum efficiency (eDQE) describes the resolution and noise properties of an imaging system along with scatter and primary transmission, all measured under clinically appropriate conditions. Effective dose efficiency (eDE) is the eDQE normalised to mean glandular dose and has been proposed as a useful metric for the optimisation of clinical imaging systems. The aim of this study was to develop a methodology for measuring eDQE and eDE on a Philips microdose mammography (MDM) L30 photon counting scanning system, and to compare performance with two conventional flat panel systems. A custom made lead-blocker was manufactured to enable the accurate determination of dose measurements, and modulation transfer functions were determined free-in-air at heights of 2, 4 and 6 cm above the breast support platform. eDQE were calculated for a Philips MDM L30, Hologic Dimensions and Siemens Inspiration digital mammography system for 2, 4 and 6 cm thick poly(methyl methacrylate) (PMMA). The beam qualities (target/filter and kilovoltage) assessed were those selected by the automatic exposure control, and anti-scatter grids were used where available. Measurements of eDQE demonstrate significant differences in performance between the slit- and scan-directions for the photon counting imaging system. MTF has been shown to be the limiting factor in the scan-direction, which results in a rapid fall in eDQE at mid-to-high spatial frequencies. A comparison with two flat panel mammography systems demonstrates that this may limit image quality for small details, such as micro-calcifications, which correlates with a more conventional image quality assessment with the CDMAM phantom. eDE has shown the scanning photon counting system offers superior performance for low spatial frequencies, which will be important for the detection of large low contrast masses. Both eDQE and eDE are proposed as useful metrics that should enable optimisation of the Philips MDM L30.
有效量子探测效率(eDQE)描述了成像系统在临床适当条件下的分辨率和噪声特性,以及散射和初级传输。有效剂量效率(eDE)是归一化到平均腺体剂量的 eDQE,已被提议作为优化临床成像系统的有用指标。本研究的目的是开发一种测量飞利浦微剂量乳腺摄影(MDM)L30 光子计数扫描系统的 eDQE 和 eDE 的方法,并将其性能与两种传统平板系统进行比较。制造了一个定制的铅阻挡器,以能够准确确定剂量测量值,并在距乳房支撑平台 2、4 和 6cm 的高度自由空气中确定调制传递函数。为飞利浦 MDM L30、Hologic Dimensions 和 Siemens Inspiration 数字乳腺摄影系统计算了 2、4 和 6cm 厚的聚甲基丙烯酸甲酯(PMMA)的 eDQE。评估的束质(靶/滤过和千伏)是自动曝光控制选择的那些,并且在可用的情况下使用了防散射格栅。eDQE 的测量结果表明,光子计数成像系统在狭缝和扫描方向之间的性能存在显著差异。MTF 已被证明是扫描方向的限制因素,这导致 eDQE 在中高空间频率处迅速下降。与两个平板乳腺摄影系统的比较表明,这可能会限制小细节(例如微钙化)的图像质量,这与使用 CDMAM 体模进行更传统的图像质量评估相关。eDE 表明,扫描光子计数系统在低空间频率下具有更好的性能,这对于检测大的低对比度肿块非常重要。eDQE 和 eDE 都被提议作为有用的指标,应该能够优化飞利浦 MDM L30。