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[-1和1在喉鳞状细胞癌中的表达及相关性]

[Expression and correlation of -1 and 1 in laryngeal squamous cell carcinoma].

作者信息

Zhang Y L, Song X F, Duan Y J, Zhao R L

机构信息

The third Department of Intensive Care Unit, the First Hospital of Shijiazhuang, Shijiazhuang 050011, China.

Department of Otorhinolaryngology, Hebei General Hospital, 050011, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Dec 7;52(12):927-932. doi: 10.3760/cma.j.issn.1673-0860.2017.12.010.

DOI:10.3760/cma.j.issn.1673-0860.2017.12.010
PMID:29262452
Abstract

To investigate the expressions of -1 1 . Immunohistochemistry and reverse transcription-polymer chain reaction (RT-PCR) were used to detect the expressions of 1 -1 47 - 21 (). . 13.0 . The positive expression rates of Fra-1 and HMGA1 proteins in laryngeal squamous cancer tissue were 48.9% and 53.2%, which were respectively higher than the rates of 19.0% for Fra-1 (χ(2)=5.416, <0.05) and of 23.8% for HMGA1 (χ(2)=5.083, <0.05) in adjacent tissues. The expression of -1 (t -1.079, -1.066 -1.067, P<0.05), (t -1.068 -1.054, P>0.05). 1 (t -1.112, -1.065, -1.009 -1.066, P<0.05), (t=-1.036, P>0.05). -1 1 (r=0.672, P<0.05). In laryngeal squamous cancer, -1 1 .

摘要

为研究-1 1的表达情况。采用免疫组织化学和逆转录-聚合酶链反应(RT-PCR)检测1 -1 47 - 21()的表达情况。13.0。喉鳞状癌组织中Fra-1和HMGA1蛋白的阳性表达率分别为48.9%和53.2%,分别高于癌旁组织中Fra-1的19.0%(χ(2)=5.416,<0.05)和HMGA1的23.8%(χ(2)=5.083,<0.05)。-1的表达(t -1.079,-1.066 -1.067,P<0.05),(t -1.068 -1.054,P>0.05)。1(t -1.112,-1.065,-1.009 -1.066,P<0.05),(t=-1.036,P>0.05)。-1 1(r=0.672,P<0.05)。在喉鳞状癌中,-1 1。

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