Going J J, Kean D M
Department of Pathology, University of Edinburgh.
J Laryngol Otol. 1989 Feb;103(2):231-3. doi: 10.1017/s0022215100108564.
Primary mucosal melanoma of the head and neck is rare and few published cases give proof that the mucosal site is primary. We present a man with malignant melanoma of the nasal cavity which was associated with melanoma-in-situ of the adjacent mucosa, proving that the lesion was primary. He presented with symptoms due to secondary deposits of melanoma in the brain rather than the more usual nose bleeds or blocked nose. The primary site was found when his neurological symptoms were investigated by CT and NMR scans of the head.
头颈部原发性黏膜黑色素瘤很罕见，鲜有已发表的病例能证明病变的黏膜部位为原发部位。我们报告一例鼻腔恶性黑色素瘤患者，其病变与相邻黏膜的原位黑色素瘤相关，证实该病变为原发性。他因黑色素瘤脑转移出现症状，而非更常见的鼻出血或鼻塞。通过对头进行CT和核磁共振扫描来调查其神经症状时，发现了原发部位。
