Wormald J C R, Park C Y, Eastwood D M
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK and Department of Orthopaedic Surgery, Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK.
Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, UK.
J Child Orthop. 2017 Dec 1;11(6):465-471. doi: 10.1302/1863-2548.11.170119.
Fractures of the lateral condyle of the humerus in children are a common injury. If displaced or unstable they may require surgical reduction and fixation with Kirschner wires (K-wires). K-wires are placed using either an open or closed technique. The decision to bury or leave the ends extending through the skin is surgeon-dependent and based on factors including post-operative infection risk, bony union and ease of wire removal.
We performed a systematic review and meta-analysis of non-buried buried K-wires for lateral condyle elbow fractures in children in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology. A comprehensive search strategy included Medline, Embase and CINAHL via NICE Evidence from database inception to June 2017. Two authors independently reviewed, included or excluded articles, extracted data and assessed for quality with the ROBINS-I tool. We performed direct comparison meta-analysis for all adverse events, post-operative infection and failure of bony union.
Three studies were analysed comprising of 434 participants. There was a significantly reduced relative risk of adverse events in the non-buried group, equating to approximately 45% reduced risk (RR 0.55, 95% confidence interval 0.34 to 0.88). There were no significant differences in risk of post-operative infection or failure of bony union. All three cost-analyses in the included studies observed savings with non-buried K-wires.
Non-buried K-wires for lateral condyle elbow fractures convey a lower risk of adverse events and may be more cost-effective compared with buried K-wires. Non-buried K-wires do not appear to increase the risk of infection or failure of bony union. These findings are limited by a high risk of bias due to inherent methodological flaws in the design of included studies.
儿童肱骨外侧髁骨折是一种常见损伤。若发生移位或不稳定,可能需要手术复位并用克氏针(K 针)固定。K 针置入可采用开放或闭合技术。决定将 K 针末端埋入还是留在皮肤外取决于外科医生,并基于包括术后感染风险、骨愈合及取针难易程度等因素。
我们按照系统评价和 Meta 分析的首选报告项目方法,对儿童肱骨外侧髁骨折采用非埋入式和埋入式 K 针进行了系统评价和 Meta 分析。全面的检索策略包括通过 NICE Evidence 从数据库建立至 2017 年 6 月检索 Medline、Embase 和 CINAHL。两位作者独立审查、纳入或排除文章、提取数据并用 ROBINS-I 工具评估质量。我们对所有不良事件、术后感染和骨不连失败进行了直接比较 Meta 分析。
分析了三项研究,共 434 名参与者。非埋入式组不良事件的相对风险显著降低,相当于风险降低约 45%(风险比 0.55,95%置信区间 0.34 至 0.88)。术后感染风险或骨不连失败无显著差异。纳入研究中的所有三项成本分析均显示非埋入式 K 针节省费用。
对于肱骨外侧髁骨折,非埋入式 K 针不良事件风险较低,与埋入式 K 针相比可能更具成本效益。非埋入式 K 针似乎不会增加感染风险或骨不连失败风险。由于纳入研究设计中存在固有的方法学缺陷,这些发现存在较高的偏倚风险。