手部创伤手术后的手术部位感染：系统评价和荟萃分析。
Surgical site infection following surgery for hand trauma: a systematic review and meta-analysis.
机构信息
Kadoorie Centre for Critical Care Research and Education, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.
Department of Burns and Plastic Surgery, Stoke Mandeville Hospital, Aylesbury, UK.
出版信息
J Hand Surg Eur Vol. 2023 Nov;48(10):998-1005. doi: 10.1177/17531934231193336. Epub 2023 Aug 22.
Surgical site infection is the most common healthcare-associated infection. Surgical site infection after surgery for hand trauma is associated with increased antibiotic prescribing, re-operation, hospital readmission and delayed rehabilitation, and in severe cases may lead to amputation. As the risk of surgical site infection after surgery for hand trauma remains unclear, we performed a systematic review and meta-analysis of all primary studies of hand trauma surgery, including randomized controlled trials, cohort studies, case-control studies and case series. A total of 8836 abstracts were screened, and 201 full studies with 315,618 patients included. The meta-analysis showed a 10% risk of surgical site infection in randomized control trials, with an overall risk of 5% when all studies were included. These summary statistics can be used clinically for informed consent and shared decision making, and for power calculations for future clinical trials of antimicrobial interventions in hand trauma.
手术部位感染是最常见的医院获得性感染。手部创伤手术后的手术部位感染与抗生素的使用增加、再次手术、住院再入院和康复延迟有关，在严重的情况下，可能导致截肢。由于手部创伤手术后手术部位感染的风险仍不清楚，我们对所有手部创伤手术的原始研究进行了系统回顾和荟萃分析，包括随机对照试验、队列研究、病例对照研究和病例系列研究。共筛选出 8836 篇摘要，纳入了 201 项完整的研究，共纳入 315618 例患者。荟萃分析显示，随机对照试验中手术部位感染的风险为 10%，当包括所有研究时，总体风险为 5%。这些汇总统计数据可用于临床知情同意和共同决策，以及未来手部创伤抗菌干预临床试验的效能计算。
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