1例怀疑头孢美唑引起的低凝血酶原血症病例。
A suspicious case of cefmetazole-induced hypoprothrombinemia.
作者信息
Kodama Nobuhiro, Matsumoto Shuichi, Matsubayashi Sunao
机构信息
Department of General Internal Medicine Fukuoka Tokushukai Medical Center Fukuoka Japan.
Department of Psychosomatic Medicine Fukuoka Tokushukai Medical Center Fukuoka Japan.
出版信息
J Gen Fam Med. 2017 Jun 21;18(5):258-260. doi: 10.1002/jgf2.18. eCollection 2017 Oct.
Abstract
Cefmetazole occasionally prolongs the prothrombin time. The mechanism is considered to be because of (i) inhibition of vitamin K metabolism, (ii) a lack of vitamin K, and (iii) low vitamin K stores. We report the death of a 93-year-old woman who was administered cefmetazole and exhibited a prolonged prothrombin time. When using cefmetazole in elderly patients, PT-INR should be monitored every few days.
摘要
头孢美唑偶尔会延长凝血酶原时间。其机制被认为是由于：（i）抑制维生素K代谢；（ii）维生素K缺乏；（iii）维生素K储备不足。我们报告了一名93岁女性的死亡病例，该患者接受了头孢美唑治疗，并出现凝血酶原时间延长。在老年患者中使用头孢美唑时，应每隔几天监测一次PT-INR。
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