Biebighauser K C, Gao Jianjun, Rao Priya, Landon Gene, Pagliaro Lance, Dinney Colin P N, Karam Jose, Navai Neema
The University of Texas Medical School at Houston, Houston, TX, USA.
Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Asian J Urol. 2017 Apr;4(2):124-127. doi: 10.1016/j.ajur.2016.08.004. Epub 2016 Aug 26.
Bone metastasis of non-seminomatous germ cell tumors (NSGCT) of the testes is a rare event and even more uncommon at initial presentation. Generally, bone lesions are discovered in the presence of concurrent retroperitoneal lymph node or visceral disease. However, in this case, a 37 years old male complaining of a growing testicular mass was found to have isolated bone metastasis with associated caudaequina syndrome without apparent abnormal findings on initial computed tomography (CT) scans. Continued neurologic symptoms prompted further evaluation with magnetic resonance imaging (MRI), which demonstrated multiple sites of bone metastasis without evidence of retroperitoneal lymph node or visceral organ involvement. This case represents a rare clinical presentation and disease manifestation of NSGCT.
睾丸非精原细胞瘤(NSGCT)的骨转移是一种罕见事件,在初次就诊时更为少见。一般来说,骨病变是在同时存在腹膜后淋巴结或内脏疾病的情况下被发现的。然而,在本病例中,一名37岁男性因主诉睾丸肿物增大就诊,被发现存在孤立性骨转移并伴有马尾综合征,初次计算机断层扫描(CT)未发现明显异常。持续的神经症状促使其进一步接受磁共振成像(MRI)检查,结果显示多处骨转移,无腹膜后淋巴结或内脏器官受累的证据。本病例代表了NSGCT一种罕见的临床表现和疾病表现。