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睾丸癌中的淋巴结成像

Lymph node imaging in testicular cancer.

作者信息

Hale Graham R, Teplitsky Seth, Truong Hong, Gold Samuel A, Bloom Jonathan B, Agarwal Piyush K

机构信息

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

Department of Urology, Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

Transl Androl Urol. 2018 Oct;7(5):864-874. doi: 10.21037/tau.2018.07.18.

Abstract

Testicular cancer is a rare malignancy mainly affecting young men. Survival for testicular cancer remains high due to the effectiveness of multimodal treatment options. Accurate imaging is imperative to both treatment and follow-up. Both computed tomography (CT) and magnetic resonance imaging (MRI) suffer from size cut-offs as the only distinguishing characteristic of benign malignant lymph nodes and may miss up to 30% of micro-metastatic disease. While functional [positron emission tomography (PET)] imaging may rule out disease in patients with seminoma who have undergone chemotherapy, there is insufficient evidence to recommend its use in other settings. This review highlights the uses and pitfalls of conventional imaging during staging, active surveillance, and post-treatment phases of both seminomatous and non-seminomatous germ cell tumors (NSGCT).

摘要

睾丸癌是一种罕见的恶性肿瘤,主要影响年轻男性。由于多模式治疗方案的有效性,睾丸癌的生存率仍然很高。准确的成像对于治疗和随访都至关重要。计算机断层扫描(CT)和磁共振成像(MRI)都存在尺寸截断问题,将其作为良恶性淋巴结的唯一区别特征,可能会漏诊高达30%的微转移疾病。虽然功能性[正电子发射断层扫描(PET)]成像可能排除接受过化疗的精原细胞瘤患者的疾病,但没有足够的证据推荐在其他情况下使用。本综述强调了传统成像在精原细胞瘤和非精原细胞瘤性生殖细胞肿瘤(NSGCT)的分期、主动监测和治疗后阶段的应用及缺陷。

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