Burgess P, Done H J
Royal Preston Hospital, Fulwood, Preston, Lancs.
J R Soc Med. 1989 Jan;82(1):28-9. doi: 10.1177/014107688908200111.
Patients presenting with adenocarcinoma of the vermiform appendix at the Royal Preston and Chorley District General Hospitals were reviewed for the 15 year period 1972-1986. Eleven cases were identified, representing a rate of 1 in 956 for all appendicectomies performed. A third of the cases presented as acute appendicitis. However, of 8 patients who initially had an appendicectomy, only 4 subsequently underwent further surgery (right hemicolectomy). One patient died of recurrent disease. Five of the patients presenting were under 60 years of age. During the same period, the total number of appendicectomies performed annually declined by 50%. The study highlights the need to subject all appendicectomy specimens to histological examination, and that the disease presents in a younger age group than commonly seen for malignant colonic neoplasms.
对1972年至1986年这15年间在皇家普雷斯顿医院和乔利地区综合医院就诊的阑尾腺癌患者进行了回顾性研究。共确诊11例,在所有阑尾切除术中的发生率为1/956。三分之一的病例表现为急性阑尾炎。然而,在最初接受阑尾切除术的8例患者中,只有4例随后接受了进一步手术(右半结肠切除术)。1例患者死于复发性疾病。就诊的患者中有5例年龄在60岁以下。在同一时期,每年进行的阑尾切除术总数下降了50%。该研究强调了对所有阑尾切除标本进行组织学检查的必要性,并且该疾病在比恶性结肠肿瘤常见年龄组更年轻的人群中出现。